Retinal oximetry and peripheral capillary non-perfusion results at baseline and 6 months follow-up.
| Baseline | 6M follow-up | Baseline–6M difference | BL–6M paired | ||
| n | Median±IQR | Median±IQR | Median±IQR | P values | |
| Peripheral capillary non-perfusion | |||||
| Global | |||||
| Inactive PDR at 6M | 23 | 26%–50% (2.0±2.3) | 26%–50% (2.0±1.6) | 0.3±0.9 | 0.38 |
| Active PDR at 6M | 10 | 51%–75% (3.3±1.3) | 51%–75% (2.9±1.3) | −0.4±1.9 | 0.87 |
| P values | 0.03* | 0.03* | 0.79 | ||
| Oximetry, % | |||||
| Arteriolar | |||||
| Inactive PDR at 6M | 23 | 96.7±5.6 | 96.8±4.7 | −0.1±5.1 | 0.92 |
| Active PDR at 6M | 10 | 93.4±6.4 | 93.3±7.2 | −1.7±2.5 | 0.02* |
| P values | 0.45 | 0.09 | 0.06 | ||
| Venular | |||||
| Inactive PDR at 6M | 23 | 67.2±12.1 | 66.2±8.3 | −1.1±15.8 | 0.69 |
| Active PDR at 6M | 10 | 63.6±14.8 | 68.7±14.7 | 1.2±5.9 | 0.16 |
| P values | 0.61 | 0.66 | 0.27 | ||
Retinal oxygen saturation and peripheral capillary non-perfusion (CNP) at baseline and follow-up month 6. Groups are compared as to inactive and active PDR at the specific time point. Peripheral CNP: 0–0.5 (close to no CNP), 1%–25% (>0.5–1.5), 26%–50% (>1.5–2.5), 51%–75% (>2.5–3.5), 76%–100% (>3.5–4.0). 6M data are corrected for rescue panretinal laser photocoagulation given to patients with active PDR at 3M (n=2).
*Statistically significant.
BL, baseline; CNP, capillary non-perfusion; PDR, proliferative diabetic retinopathy; 6M, 6 months’ follow-up.