T category | Time to outcomes of interest | ||||
Local recurrence | Lymph node metastasis† | Distant metastasis | Death from disease | Death from any cause | |
T1 vs T2‡ | – | 0.23 | 0.21 | – | 0.31 |
T1 vs T3 | 0.02 | 0.03 | 0.32 | 0.31 | 0.28 |
T1 vs T4 | 0.05 | <0.01 | <0.01 | <0.01 | <0.01 |
T2 vs T3 | 0.10 | 0.11 | 0.77 | 0.45 | 0.18 |
T2 vs T4 | 0.11 | 0.10 | <0.01 | <0.01 | <0.01 |
T3 vs T4 | 0.9 | 0.45 | <0.01 | <0.01 | 0.01 |
T1/T2 vs T3/T4 | 0.01 | 0.01 | 0.01 | 0.01 | 0.01 |
*P values are not adjusted for multiple comparisons owing to the exploratory nature of the study.
†Lymph node metastasis during follow-up (not at presentation) was the subject of analysis.
‡Neither local recurrence nor death from disease occurred in patients with T1 and T2 disease; p values cannot be computed for these outcomes.