Table 1

Summary of clinical measures expressed as median (IQR)

Controls
(early and no AMD, n=8)
Intermediate AMD
(n=7)
GA
(n=15)
P value
Age, years77 (72, 80)82 (70, 86)75 (70, 78)0.20
Binocular VA0.04 (−0.04, 0.18)0.26 (0.10, 0.40)0.32 (0.20, 0.56)0.01
Better eye VA0.10 (0.00, 0.18)0.26 (0.20, 0.42)0.36 (0.32, 0.60)<0.01
Worse eye VA0.28 (0.06, 0.42)0.58 (0.26, 1.58)0.86 (0.40, 1.02)0.01
CS1.95 (1.65, 1.95)1.60 (1.35, 1.65)1.60 (1.25, 1.65)0.01
Better eye AT27.8 (26.1, 29.8)26.5 (25.8, 27.8)23.4 (19.0, 25.6)<0.01
Worse eye AT27.0 (25.6, 29.5)25.0 (23.8, 27.4)20.4 (6.9, 23.8)<0.01
EQ-5D index score0.89 (0.72, 1.00)0.81 (0.72, 1.00)0.77 (0.72, 1.00)0.57
  • P values for between-group differences were calculated using Kruskal-Wallis tests.

  • AMD, age-related macular degeneration; AT, MAIA microperimetry average threshold; CS, Pelli-Robson contrast sensitivity (logCS);GA, geographic atrophy; VA, visual acuity (logMAR).