Items of a question-based survey and results of survey responses of the sixth IWOS
| Items | Agree | Disagree | %Agreement |
| I. Other causes of granulomatous uveitis must be ruled out | 24 | 4 | 83 |
| II. Intraocular clinical signs suggestive of OS | |||
| 1. Mutton-fat keratic precipitates and/or iris nodules (Koeppe or Busacca) | 30 | 0 | 100 |
| 2. Trabecular meshwork nodules and/or tent-shaped peripheral anterior synechia | 28 | 2 | 93 |
| 3. Snowballs/string of pearls vitreous opacities | 28 | 2 | 93 |
| 4.Multiple chorioretinal peripheral lesions (active and atrophic) | 29 | 1 | 97 |
| 5. Periphlebitis and/or macroaneurysm in an inflamed eye | 27 | 3 | 90 |
| 6. Opticdisc nodule(s)/granuloma(s) and/or choroidal nodule | 29 | 1 | 97 |
| 7. Bilaterality (clinically or by imaging) | 20 | 8 | 71 |
| III. Systemic investigations in suspected OS | |||
| 1. BHL by chest X-ray or chest computed CT scan | 30 | 0 | 100 |
| 2. Negative tuberculin test or IGRA | 27 | 3 | 93 |
| 3. Elevated serum ACE | 28 | 2 | 93 |
| 4. Elevated serum lysozyme | 23 | 7 | 77 |
| 5. Elevated serum soluble IL-2 receptor | 20 | 9 | 69 |
| 6. Elevated serum calcium | 19 | 11 | 63 |
| 7. Elevated serum gamma-globulin | 14 | 16 | 47 |
| 8. Elevated serum KL-6 | 14 | 15 | 48 |
| 9. Elevated CD4/CD8 ratio (>3.5) in BAL fluid | 26 | 4 | 87 |
| 10. Abnormal 67-gallium scintigraphy or 18F-FDG PET | 27 | 3 | 90 |
| IV. Diagnostic criteria | |||
| Definite OS: diagnosis supported by biopsy with compatible uveitis | 30 | 0 | 100 |
| Presumed OS: diagnosis not supported by biopsy, but BHL present with two intraocular signs | 24 | 6 | 80 |
| Probable OS: diagnosis not supported by biopsy and BHL absent, but three intraocular signs and two systemic investigations selected from two to eight are present | 20 | 10 | 67 |
BAL, bronchoalveolar lavage; BHL, bilateral hilar lymphadenopathy; CD, cluster of differentiation; FDG PET, fluorodeoxyglucose positron emission tomography; IGRA, interferon-gamma releasing assays; IL, interleukin; IWOS, International Workshop on Ocular Sarcoidosis; KL, Krebs von den Lungen; OS, ocular sarcoidosis.