Table 1

Baseline participant characteristics

Formulated eye drop (n=21)Control eye drop (n=21)P value
Age (years)22.2±3.520.6±3.20.12
Gender (M:F)9:125:16
Inferior LLT (nm)68.9±23.268.5±19.20.96
TER (gm−2h)41.7±13.735.9±12.50.18
TBUT (s)5.1±1.86.0±2.90.13
Corneal staining (0–4)0.5±0.50.3±0.40.16
OSDI (0–100)33.7±12.428.2±12.30.15
Symptoms (0–100)*
 Burning/stinging23.3±21.622.9±23.40.74
 Grittiness/foreign body sensation37.1±26.629.0±27.00.26
 Dryness59.2±24.555.9±24.60.57
 Blurry vision22.9±23.938.9±31.30.08
 Overall discomfort27.3±22.324.6±26.70.52
  • *0=none, 100=maximum.

  • LLT, lipid layer thickness; OSDI, Ocular Surface Disease Index; TBUT, tear break-up time; TER, tear evaporation rate.