Area under the receiver operating characteristic (AUROC) curve analyses of the FAZ metrics, parafoveal capillary density and per cent area deviated from normal distribution in differentiating eyes without SCR (control) and eyes with SCR (NP-SCR and P-SCR)
Measurements | AUROC (95% CI) | |
FAZ | Area | 0.58 (0.43 to 0.73) |
Perimeter | 0.69 (0.57 to 0.82) | |
Acircularity index | 0.82 (0.72 to 0.92) | |
Parafoveal capillary density | Entire image | 0.87 (0.78 to 0.96) |
Temporal | 0.86 (0.77 to 0.95) | |
Nasal | 0.85 (0.76 to 0.94) | |
Superior | 0.85 (0.76 to 0.94) | |
Inferior | 0.83 (0.72 to 0.94) | |
Per cent yellow area | Entire image | 0.85 (0.75 to 0.94) |
Temporal | 0.86 (0.76 to 0.95) | |
Nasal | 0.81 (0.71 to 0.91) | |
Superior | 0.84 (0.74 to 0.94) | |
Inferior | 0.73 (0.61 to 0.85) | |
Per cent red area | Entire image | 0.84 (0.75 to 0.94) |
Temporal | 0.82 (0.73 to 0.92) | |
Nasal | 0.83 (0.72 to 0.93) | |
Superior | 0.82 (0.72 to 0.92) | |
Inferior | 0.73 (0.59 to 0.86) |
CI, confidence interval; FAZ, foveal avascular zone; NP-SCR, non-proliferative SCR; P-SCR, proliferative SCR; SCR, sickle cell retinopathy.