Table 2

Five-year changes of AS-OCT parameters in dark and light-to-dark during the follow-up

ParameterBaseline measurementFollow-up
measurement
Mean difference
(95% CI)*
P value
In dark condition
TISA500, mm2 0.077±0.050.082±0.05−0.005 (-0.015 to 0.004)0.287
ARA750, mm2 0.158±0.1010.164±0.091−0.006 (−0.026 to −0.013)0.548
IT750, mm0.450±0.1760.473±0.897−0.023 (−0.05 to −0.006)0.119
Iarea, mm2 1.569±0.4841.537±0.2260.031 (−0.046 to −0.108)0.431
ACW, mm11.74±0.4411.60±0.370.141 (0.058 to 0.224) 0.001
ACA, mm2 18.94±2.8918.51±2.940.426 (−0.168 to 1.020)0.160
LV,μm573.5±246.2551.7±266.721.772 (−30.56 to 74.11)0.414
PD, mm4.32±1.144.44±0.69−0.124 (−0.315 to 0.068)0.205
Light-to-dark changes
ΔTISA500, mm2 0.022±0.0320.023±0.031−0.001 (−0.007 to 0.006)0.822
ΔARA, mm2 −0.045±0.065−0.049±0.067−0.004 (−0.017 to 0.009)0.521
ΔIT750, mm−0.075±0.166−0.032±0.081−0.044 (−0.070 to −0.167) 0.001
ΔIarea, mm2 0.270±0.4140.262±0.1830.009 (−0.056 to 0.075)0.784
ΔACW, mm0.052±0.197−0.006±0.1660.057 (0.020 to 0.094) 0.003
ΔACA, mm2 −0.709±0.271−0.589±0.273−0.118 (−0.174 to -0.062) < 0.001
ΔLV, μm20.4±70.915.996±75.964.4 (−10.5 to 19.3)0.564
ΔPD, mm−1.7±1.1−1.3±0.9−0.42 (−0.63 to -0.22) < 0.001
  • Bold indicates statistical significance.

  • *Parameters in 2008 minus those in 2013.

  • ACA, anterior chamber area; ACW, anterior chamber width; ARA, angle recess area;AS-OCT, anterior segment optical coherence tomography; IT750, iris thickness at 750 µm; Iarea, iris area; LV, lens vault; PD, pupil diameter; TISA500, trabecular iris space area at 500 µm.