Table 4

Univariate and multivariate linear mixed-effect model determination of factors associated with changes of AL in patients with high myopia

UnivariateMultivariate
Estimate (95% CI)P valueEstimate (95% CI)P value
Age0.038 (0.002 to 0.074) 0.040 0.001 (−1.262 to 0.003)0.942
Sex−0.286 (−1.336 to 0.765)0.588
BCVA−3.011 (−5.077 to −0.946) 0.005 0.118 (−0.037 to 0.273)0.133
Keratometry−0.025 (−0.272 to 0.223)0.843
IOP−0.162 (−0.382 to 0.058)0.146
Baseline AL1.024 (1.007 to 1.041) < 0.001 1.032 (1.010 to 1.053) < 0.001
Baseline ACD1.512 (0.452 to 2.752) 0.006 −0.023 (−0.102 to 0.056)0.568
Baseline RCC0.042 (−1.214 to 1.300)0.947
  • Values in bold face (p<0.05) are statistically significant.

  • In multivariate analyses, only baseline AL showed a significant association (p<0.001).

  • ACD, anterior chamber depth; AL, axial length; BCVA, best-corrected visual acuity; IOP, intraocular pressure; RCC, radius of corneal curvature; SE, spherical equivalent.