Demographics and anterior segment quantitative parameters of true negatives and false negatives, at different cut-off values of circumferential angle closure assessed by swept-source optical coherence tomography
| Variable mm, mean (SD) (95% CI) | ≥35% | ≥50% | ≥75% | |||
| True negative n=1353 | False negative n=25 | True negative n=1453 | False negative n=34 | True negative n=1566 | False negative n=55 | |
| Age (years) | 61.22 (6.75) | 58.72 (8.11) | 61.08 (6.75) | 60.36 (7.85) | 61.24 (6.72) | 62.83 (7.25) |
| Gender (male:female), n (%) | 523 (38.70):830 (61.30) | 7 (28.0):18 (72.0) | 551 (37.90):902 (62.10) | 8 (23.50):26 (76.50) | 587 (37.5):979 (62.5) | 11 (20.0):44 (80.0)** |
| Ethnicity (Chinese:non-Chinese), n (%) | 1170 (86.50):183 (13.50) | 21 (84.0):4 (16.0) | 1258 (86.60):195 (13.40) | 28 (82.40):6 (17.60) | 1365 (87.2):201 (12.8) | 49 (89.1):6 (10.9) |
| ACD | 2.73 (0.31) (2.71 to 2.75) | 2.30 (0.24)** (2.21 to 2.39) | 2.72 (0.31) (2.7 to 2.74) | 2.19 (0.23)** (2.11 to 2.27) | 2.69 (0.31) (2.67 to 2.71) | 2.20 (0.22)** (2.14 to 2.26) |
| ACW | 11.84 (0.49) (11.81 to 11.87) | 11.58 (0.42)* (11.42 to 11.74) | 11.83 (0.48) (11.81 to 11.85) | 11.56 (0.44)** (11.41 to 11.71) | 11.81 (0.47) (11.79 to 11.83) | 11.53 (0.42)
**
(11.42 to 11.64) |
| PD | 3.50 (0.79) (3.46 to 3.54) | 3.45 (0.75) (3.16 to 3.74) | 3.51 (0.79) (3.47 to 3.55) | 3.44 (0.72) (3.2 to 3.68) | 3.54 (0.79) (3.5 to 3.58) | 3.42 (0.70) (3.23 to 3.61) |
| ACA | 20.31 (3.20) (20.14 to 20.48) | 15.76 (2.71)** (14.7 to 16.82) | 20.12 (3.22) (19.95 to 20.29) | 15.37 (2.58)** (14.5 to 16.24) | 19.91 (3.23) (19.75 to 20.07) | 15.21 (2.37)** (14.58 to 15.84) |
| IV | 37.18 (4.38) (36.95 to 37.41) | 35.68 (4.01) (34.11 to 37.25) | 37.17 (4.38) (36.94 to 37.4) | 36.18 (3.73) (34.93 to 37.43) | 37.14 (4.37) (36.92 to 37.36) | 35.15 (4.19)* (34.04 to 36.26) |
| LV | 0.40 (0.24) (0.39 to 0.41) | 0.70 (0.15)** (0.64 to 0.76) | 0.40 (0.24) (0.39 to 0.41) | 0.80 (0.17)** (0.74 to 0.86) | 0.40 (0.24) (0.39 to 0.41) | 0.80 (0.15)** (0.76 to 0.84) |
*P<0.05, **P<0.01, Student’s t-test or Fisher’s exact test comparing true negatives and false negatives.
ACA, anterior chamber area; ACD, anterior chamber depth; ACW, anterior chamber width; IV, iris volume; LV, lens vault; PD, pupil diameter.