Factors associated with poor visual outcome among children with bilateral cataract (defined as best corrected visual acuity of less than 0.48 in the better eye at 1 year) (n=154)
| Variables | Total (n=154) | Poor outcome (n=72) | Unadjusted analysis | Adjusted analysis | ||||
| OR | (95% CI) | P value | OR | (95% CI) | P value | |||
| Age at surgery | n (%) | |||||||
| ≤24 months | 78 | 52 (66.7) | 1.00 | – | – | 1.00 | ||
| >24 months | 76 | 20 (26.3) | 0.18 | 0.08 to 0.38 | <0.001 | 0.39 | 0.14 to 1.10 | 0.076 |
| Delayed presentation/lag time | ||||||||
| ≤3 months | 28 | 15 (53.6) | 1.00 | – | – | |||
| >3 to ≤12 months | 57 | 31 (54.4) | 1.03 | 0.41 to 2.57 | 0.945 | |||
| >12 months | 65 | 23 (35.4) | 0.47 | 0.29 to 3.32 | 0.104 | |||
| Missing | 4 | 3 (75.0) | ||||||
| Preoperative blindness | ||||||||
| No | 38 | 4 (10.5) | 1.00 | – | – | 1.00 | ||
| Yes | 116 | 68 (58.6) | 12.04 | 3.58 to 40.51 | <0.001 | 14.65 | 2.21 to 97.20 | 0.005 |
| Preoperative nystagmus/strabismus | ||||||||
| No | 50 | 7 (14.0) | 1.00 | – | – | 1.00 | ||
| Yes | 105 | 65 (61.9) | 10.24 | 3.75 to 27.97 | <0.001 | 9.22 | 2.66 to 31.97 | <0.001 |
| Microphthalmos | ||||||||
| No | 119 | 48 (40.3) | 1.00 | – | – | 1.00 | ||
| Yes | 28 | 20 (71.4) | 3.69 | 1.46 to 9.37 | 0.003 | 1.12 | 0.29 to 4.29 | 0.872 |
| Missing | 7 | 4 (57.1) | ||||||
| Aphakia | ||||||||
| No | 128 | 50 (39.1) | 1.00 | – | – | 1.00 | ||
| Yes | 26 | 22 (84.6) | 8.58 | 2.59 to 28.46 | <0.001 | 5.32 | 1.05 to 26.97 | 0.043 |
| Astigmatism | ||||||||
| No | 109 | 58 (45.9) | 1.00 | – | – | 1.00 | ||
| Yes | 33 | 11 (33.3) | 0.44 | 0.19 to 1.01 | 0.046 | 0.91 | 0.29 to 2.79 | 0.865 |
| Missing | 12 | 3 (25.0) | ||||||
| Cataract grade | ||||||||
| Grade ≤7 | 22 | 3 (13.6) | 1.00 | 1.00 | ||||
| Grade 8–10 | 132 | 69 (52.3) | 6.90 | 1.86 to 25.92 | <0.001 | 0.45 | 0.03 to 6.07 | 0.548 |
| Refractive error | ||||||||
| Myopia (≥−1.5 D) | 38 | 14 (36.8) | 1.00 | |||||
| Hypermetropia (>1.0 D) | 43 | 21 (48.8) | 1.64 | 0.66 to 4.03 | 0.280 | |||
| Missing/emmetropia | 73 | 37 (50.7) | ||||||
| High myopia (>−4.0 D) | ||||||||
| No | 108 | 43 (39.9) | 1.00 | |||||
| Yes | 10 | 4 (40.0) | 1.01 | 0.27 to 3.80 | 0.991 | |||
| Missing | 36 | 25 (69.4) | ||||||
| High hypermetropia (>4.0 D) | ||||||||
| No | 103 | 38 (39.9) | 1.00 | |||||
| Yes | 15 | 9 (60.0) | 2.57 | 0.83 to 7.91 | 0.089 | |||
| Missing | 36 | 25 (69.4) | ||||||
| Early postoperative complications | ||||||||
| No | 125 | 54 (43.2) | 1.00 | |||||
| Yes | 29 | 18 (62.1) | 2.15 | 0.93 to 4.99 | 0.07 | |||
| Late postoperative complications | ||||||||
| No | 132 | 63 (47.7) | 1.00 | |||||
| Yes | 22 | 9 (40.9) | 0.76 | 0.30 to 1.90 | 0.55 | |||
| Keratometry performed | ||||||||
| No | 50 | 23 (46.0) | 1.00 | |||||
| Yes | 104 | 49 (47.1) | 1.05 | 0.53 to 2.06 | 0.89 | |||
| Systemic problem | ||||||||
| No | 97 | 43 (44.3) | 1.00 | |||||
| Yes | 57 | 29 (50.9) | 1.30 | 0.67 to 2.51 | 0.43 | |||
| Anaemia | ||||||||
| No | 76 | 30 (39.5) | 1.00 | 1.00 | ||||
| Yes | 74 | 41 (55.4) | 1.91 | 0.98 to 3.69 | 0.05 | 0.86 | 0.32 to 2.31 | 0.765 |
| Missing | 4 | 1 (25.0) | ||||||
Bold type denotes statisticaly significant values.