Table 2

Schedule of assessments

Baseline6 months12 months18 months24 months
Adverse events ✔ ✔ ✔ ✔
Tolerability ✔ ✔ ✔ ✔
EQ-5D-Y Questionnaire ✔ ✔ ✔ ✔ ✔
Activities questionnaire – to be sent home with participant for completion ✔ ✔ ✔ ✔ ✔
Best-corrected VA (logMAR ETDRS) ✔ ✔ ✔ ✔ ✔
Near VA (near logMAR ETDRS) ✔ ✔ ✔ ✔ ✔
Iris colour ✔
Reading speed (Wilkins Rate of Reading Test) ✔ ✔ ✔ ✔ ✔
Pupil diameter prior to cycloplegia (autorefractor) ✔ ✔ ✔ ✔ ✔
Accommodation (autorefractor) ✔ ✔ ✔ ✔ ✔
Peripheral retinal defocus (autorefractor) ✔ ✔ ✔
Anterior chamber depth (laser biometer) ✔ ✔ ✔ ✔ ✔
Cycloplegic refractive error (autorefractor) ✔ ✔ ✔ ✔ ✔
Ciliary body biometry (AS-OCT)* ✔ ✔ ✔
Central axial length (laser biometer) ✔ ✔ ✔ ✔ ✔
Peripheral axial length (laser biometer) ✔ ✔ ✔
Chorioretinal thickness (SD-OCT) ✔ ✔ ✔ ✔ ✔

  • ✔✔ means before and after cycloplegia.

  • *If instrumentation is available.

  • VA, visual acuity.