OSDI with the three subset score (sub A, B, C), VAS score, Schirmer test, tear break up time (TBUT) and conjunctival staining score before (V2) and after (V4) 1-month CBS and PBS treatment. No change was observed for the Schirmer test and TBUTvalues, whereas a reduction was shown for OSDI, conjunctival staining and VAS, but without a statistically significant difference between treatments. Among OSDI subset scores, only sub A significantly lowered in the CBS treated group as compared with the PBS treated group (p=0.03). Values expressed as median (95% CI)
| CBS | PBS | ||
| V2 | V4 | V2 | V4 |
| OSDI score | OSDI score | ||
| 52 (47–60) | 31 (28-37) | 48 (38–59) | 38 (29-44) |
| SUB A 24 (13–30) | 15 (10–16) | 28 (20–32) | 21 (14–34) |
| SUB B 13 (8–19) | 8 (4–10) | 12 (8–14) | 8 (4–14) |
| SUB C 14 (10–20) | 11 (6–18) | 12 (8–20) | 8 (6–20) |
| VAS score | VAS score | ||
| 7.4 (6.5–7.8) | 5.0 (4.5–5.8) | ||
| Schirmer test | Schirmer test | ||
| 5.0 (4.1–7.0) | 5.0 (3.1–6.8) | 4.0 (2.7–6.2) | 5.0 (4.0–6.0) |
| TBUT | TBUT | ||
| 3.0 (2.0–4.0) | 3.0 (2.0–4.2) | 3.0 (1.0–4.0) | 2.5 (2.0–4.0) |
| Conjunctival staining score | Conjunctival staining score | ||
| 9.0 (6.0–11.0) | 6.0 (3.0–7.4) | 11.0 (7.0–12.0) | 7.0 (5.0–9.0) |
CBS, cord blood serum; OSDI, Ocular Surface Disease Index; PBS, peripheral blood serum; TBUT, Tear Break Up Time; VAS, Visual Analogue Score.