Table 3

OSDI with the three subset score (sub A, B, C), VAS score, Schirmer test, tear break up time (TBUT) and conjunctival staining score before (V2) and after (V4) 1-month CBS and PBS treatment. No change was observed for the Schirmer test and TBUTvalues, whereas a reduction was shown for OSDI, conjunctival staining and VAS, but without a statistically significant difference between treatments. Among OSDI subset scores, only sub A significantly lowered in the CBS treated group as compared with the PBS treated group (p=0.03). Values expressed as median (95% CI)

CBSPBS
V2V4V2V4
OSDI score OSDI score
 52 (47–60)31 (28-37) 48 (38–59)38 (29-44)
 SUB A 24 (13–30)15 (10–16) 28 (20–32)21 (14–34)
 SUB B 13 (8–19)8 (4–10) 12 (8–14)8 (4–14)
 SUB C 14 (10–20)11 (6–18) 12 (8–20)8 (6–20)
VAS score VAS score
 7.4 (6.5–7.8) 5.0 (4.5–5.8)
Schirmer test Schirmer test
 5.0 (4.1–7.0)5.0 (3.1–6.8) 4.0 (2.7–6.2)5.0 (4.0–6.0)
TBUT TBUT
 3.0 (2.0–4.0)3.0 (2.0–4.2) 3.0 (1.0–4.0)2.5 (2.0–4.0)
Conjunctival staining score Conjunctival staining score
 9.0 (6.0–11.0)6.0 (3.0–7.4) 11.0 (7.0–12.0)7.0 (5.0–9.0)
  • CBS, cord blood serum; OSDI, Ocular Surface Disease Index; PBS, peripheral blood serum; TBUT, Tear Break Up Time; VAS, Visual Analogue Score.