Characteristic | No prescription of PPS (n=15 060) | Had prescription of PPS (n=3012) | P value |
Age, Mean in years (SD) | 52.3 (15.7) | 52.3 (15.7) | 0.98* |
Sex, Female | 12 645 (84%) | 2529 (84%) | 1.00† |
Race | 1.00† | ||
White | 10 685 (71%) | 2137 (71%) | |
Black | 1210 (8%) | 242 (8%) | |
Hispanic | 2035 (14%) | 407 (14%) | |
Asian | 325 (2%) | 65 (2%) | |
Unknown | 805 (5%) | 161 (5%) | |
Index year | 1.00† | ||
2002 | 225 (1%) | 45 (1%) | |
2003 | 795 (5%) | 159 (5%) | |
2004 | 1060 (7%) | 212 (7%) | |
2005 | 2155 (14%) | 431 (14%) | |
2006 | 1810 (12%) | 362 (12%) | |
2007 | 1995 (13%) | 399 (13%) | |
2008 | 2105 (14%) | 421 (14%) | |
2009 | 1900 (13%) | 380 (13%) | |
2010 | 1575 (10%) | 315 (10%) | |
2011 | 1440 (10%) | 288 (10%) | |
Diagnosis | |||
Diabetes | 1565 (10%) | 322 (11%) | 0.62† |
Past stroke or transient ischaemic attack | 379 (3%) | 91 (3%) | 0.11† |
Peripheral vascular disease | 719 (5%) | 224 (7%) | <0.001† |
Malignancy | 788 (5%) | 300 (10%) | <0.001† |
Chronic kidney disease | 260 (2%) | 78 (3%) | 0.001† |
Atrial fibrillation/flutter | 296 (2%) | 74 (2%) | 0.08† |
Congestive heart failure | 430 (3%) | 95 (3%) | 0.37† |
Previous myocardial infarction | 381 (3%) | 117 (4%) | <0.001† |
Arrhythmia | 1066 (7%) | 323 (11%) | <0.001† |
Hypertension | 4366 (29%) | 983 (33%) | <0.001† |
*Equal variance t-test.
†χ2 test.
PPS, pentosan polysulfate sodium.