Baseline participant characteristics
Formulated eye drop (n=21) | Control eye drop (n=21) | P value | |
Age (years) | 22.2±3.5 | 20.6±3.2 | 0.12 |
Gender (M:F) | 9:12 | 5:16 | – |
Inferior LLT (nm) | 68.9±23.2 | 68.5±19.2 | 0.96 |
TER (gm−2h) | 41.7±13.7 | 35.9±12.5 | 0.18 |
TBUT (s) | 5.1±1.8 | 6.0±2.9 | 0.13 |
Corneal staining (0–4) | 0.5±0.5 | 0.3±0.4 | 0.16 |
OSDI (0–100) | 33.7±12.4 | 28.2±12.3 | 0.15 |
Symptoms (0–100)* | |||
Burning/stinging | 23.3±21.6 | 22.9±23.4 | 0.74 |
Grittiness/foreign body sensation | 37.1±26.6 | 29.0±27.0 | 0.26 |
Dryness | 59.2±24.5 | 55.9±24.6 | 0.57 |
Blurry vision | 22.9±23.9 | 38.9±31.3 | 0.08 |
Overall discomfort | 27.3±22.3 | 24.6±26.7 | 0.52 |
*0=none, 100=maximum.
LLT, lipid layer thickness; OSDI, Ocular Surface Disease Index; TBUT, tear break-up time; TER, tear evaporation rate.