Table 2

Change and change difference of SER and AL in three groups over 1 year*

Variables	Mean (95% CI)
	0.02% atropine		0.01% atropine		Control group		Change difference between-group
	Baseline	12 months change	Baseline	12 months change	Baseline	12 months change	0.02% vs 0.01% atropine	P value	0.01% atropine vs control group	P value
SER	−2.76 (−2.86 to −2.66)	−0.11† (−0.17 to −0.05)	−2.70 (−2.81 to 2.69)	−0.15† (−0.21 to −0.09)	−2.68 (−2.78 to −2.58)	−0.23† (−0.28 to −0.17)	0.04 (0.01 to 0.07)	0.04	0.09 (0.02 to 0.16)	0.01
AL	24.60 (24.46 to 24.74)	0.30† (0.25 to 0.35)	24.58 (24.44 to 24.72)	0.35† (0.31 to 0.39)	24.55 (24.40 to 24.70)	0.49† (0.43 to 0.55)	0.04 (0.01 to 0.07)	0.03	0.14 (0.19 to 0.09)	0.004

Change represents the slope of SER and AL over time for three groups. Change difference represents the difference in slope of SER and AL over time between the two groups.
*A generalised additive mixed model was used to estimate the longitudinal trend from baseline to 12 months. A significant increase was shown in change in SER and AL in three groups from baseline to 12 months.
†Changes were significantly different.
AL, axial length; SER, spherical equivalent refractive error.