Table 2

Change and change difference of SER and AL in three groups over 1 year*

VariablesMean (95% CI)
0.02% atropine0.01% atropineControl groupChange difference between-group
Baseline12 months changeBaseline12 months changeBaseline12 months change0.02% vs
0.01% atropine
P value0.01% atropine vs control groupP value
SER−2.76
(−2.86 to −2.66)
−0.11†
(−0.17 to −0.05)
−2.70
(−2.81 to 2.69)
−0.15†
(−0.21 to −0.09)
−2.68
(−2.78 to −2.58)
−0.23†
(−0.28 to −0.17)
0.04
(0.01 to 0.07)
0.040.09
(0.02 to 0.16)
0.01
AL24.60
(24.46 to 24.74)
0.30†
(0.25 to 0.35)
24.58
(24.44 to 24.72)
0.35†
(0.31 to 0.39)
24.55
(24.40 to 24.70)
0.49†
(0.43 to 0.55)
0.04
(0.01 to 0.07)
0.030.14
(0.19 to 0.09)
0.004
  • Change represents the slope of SER and AL over time for three groups. Change difference represents the difference in slope of SER and AL over time between the two groups.

  • *A generalised additive mixed model was used to estimate the longitudinal trend from baseline to 12 months. A significant increase was shown in change in SER and AL in three groups from baseline to 12 months.

  • †Changes were significantly different.

  • AL, axial length; SER, spherical equivalent refractive error.