Change and change difference of SER and AL in three groups over 1 year*
Variables | Mean (95% CI) | |||||||||
0.02% atropine | 0.01% atropine | Control group | Change difference between-group | |||||||
Baseline | 12 months change | Baseline | 12 months change | Baseline | 12 months change | 0.02% vs 0.01% atropine | P value | 0.01% atropine vs control group | P value | |
SER | −2.76 (−2.86 to −2.66) | −0.11† (−0.17 to −0.05) | −2.70 (−2.81 to 2.69) | −0.15† (−0.21 to −0.09) | −2.68 (−2.78 to −2.58) | −0.23† (−0.28 to −0.17) | 0.04 (0.01 to 0.07) | 0.04 | 0.09 (0.02 to 0.16) | 0.01 |
AL | 24.60 (24.46 to 24.74) | 0.30† (0.25 to 0.35) | 24.58 (24.44 to 24.72) | 0.35† (0.31 to 0.39) | 24.55 (24.40 to 24.70) | 0.49† (0.43 to 0.55) | 0.04 (0.01 to 0.07) | 0.03 | 0.14 (0.19 to 0.09) | 0.004 |
Change represents the slope of SER and AL over time for three groups. Change difference represents the difference in slope of SER and AL over time between the two groups.
*A generalised additive mixed model was used to estimate the longitudinal trend from baseline to 12 months. A significant increase was shown in change in SER and AL in three groups from baseline to 12 months.
†Changes were significantly different.
AL, axial length; SER, spherical equivalent refractive error.