Association between the preoperative FAZ area and ocular variables: univariate and multivariable analyses (n=108 eyes)
| Preoperative FAZ area, mm2 | ||||||
|---|---|---|---|---|---|---|
| Univariate model | Multivariate model 1 | Multivariate model 2 | ||||
| Variables | Coefficients | P value | Coefficients | P value | Coefficients | P value |
| (95% CI) | (95% CI) | (95% CI) | ||||
| Age (years) per 10 years | 0.020 (−0.014 to 0.053) | 0.254 | −0.006 (−0.038 to 0.026) | 0.751 | −0.003 (−0.036 to 0.03) | 0.860 |
| Sex (male/female) | 0.058 (−0.017 to 0.133) | 0.129 | ||||
| CCT (μm) per 100 μm | −0.152 (−0.25 to −0.054) | 0.002* | −0.113 (−0.214 to −0.013) | 0.036** | −0.12 (−0.22 to −0.019) | 0.019** |
| Axial length (mm) per 1 mm | 0.033 (−0.194 to 0.259) | 0.777 | ||||
| Preoperative IOP (mmHg) per 10 mmHg | 0.013 (−0.024 to 0.049) | 0.496 | ||||
| HFA 24-2 MD (dB) per 10 dB | −0.040 (−0.069 to −0.01) | 0.008 | −0.006 (−0.039 to 0.026) | 0.701 | 0.015 (−0.029 to 0.058) | 0.512 |
| Foveal Sensitivity (1/Lambert) per 1000 unit | −0.032 (−0.047 to −0.017) | <0.001* | −0.022 (−0.039 to −0.005) | 0.012** | ||
| Central-4point mean sensitivity (1/Lambert) per 1000 unit | −0.057 (−0.085 to −0.029) | <0.001* | −0.057 (−0.101 to −0.012) | 0.013** | ||
| Topical glaucoma medications (yes/no) | ||||||
| β-Blocker | 0.049 (−0.017 to 0.115) | 0.144 | ||||
| PG analogue | 0.084 (0.011 to 0.158) | 0.025* | 0.039 (−0.04 to 0.118) | 0.337 | 0.019 (−0.057 to 0.096) | 0.619 |
| CAI | 0.041 (−0.024 to 0.107) | 0.218 | ||||
| α-Agonists | 0.011 (−0.051 to 0.073) | 0.729 | ||||
| ROCK inhibitor | 0.024 (−0.036 to 0.084) | 0.436 | ||||
*p<0.10, univariate analysis.
**p<0.05, multivariate analysis.
CAI, carbonic anhydrase inhibitors; CCT, central corneal thickness; FAZ, foveal avascular zone; HFA, Humphrey field analyser; IOP, intraocular pressure; MD, mean deviation; PG, prostaglandin; ROCK, Rho-associated coiled-coil-containing protein kinase.