Table 2

Correlations of best Snellen corrected visual acuity (BCVA), mean deviation (MD) and center foveal thickness (CFT) with age and disease duration in patients with USH2A mutations

	BCVA		MD		CFT
	R value	P value	R value	P value	R value	P value
Age*	−0.323	<0.001	−0.015	0.434	−0.199	0.023
RP	−0.207	0.016	−0.149	0.129	−0.312	0.018
Ages
≤50, years	−0.032	0.397	−0.294	0.035	−0.095	0.308
>50, years	−0.290	0.041	−0.605	0.003	−0.209	0.236
Durations
≤10 years	−0.032	0.438	−0.120	0.312	−0.087	0.418
10–20 years	−0.433	0.041	−0.590	0.082	−0.688	0.003
>20 years	−0.285	0.013	−0.104	0.290	−0.437	0.024
USH2	−0.431	<0.001	−0.357	0.002	−0.182	0.092
Ages
≤50	−0.277	0.003	−0.132	0.172	−0.228	0.062
>50	−0.387	0.019	−0.803	0.005	−0.246	0.297
Durations
≤10 years	−0.376	0.032	−0.085	0.381	−0.542	0.028
10–20 years	−0.401	0.010	−0.471	0.052	−0.318	0.08
>20 years	−0.490	<0.001	−0.456	0.004	−0.527	0.01
Duration†	−0.182	0.002	−0.250	0.003	−0.036	0.362
RP	−0.272	0.002	−0.451	<0.001	−0.078	0.306
Ages
≤50, years	−0.405	<0.001	−0.406	0.005	−0.007	0.485
>50, years	−0.030	0.431	−0.317	0.093	−0.147	0.308
Durations
≤10 years	−0.105	0.301	−0.364	0.063	−0.377	0.179
10–20 years	−0.374	0.070	−0.867	0.006	−0.363	0.101
>20 years	−0.080	0.270	−0.088	0.319	−0.475	0.015
USH2	−0.062	0.243	−0.107	0.202	−0.007	0.480
Ages
≤50, years	−0.038	0.353	−0.096	0.247	−0.056	0.353
>50, years	−0.146	0.225	−0.177	0.324	−0.288	0.265
Durations
≤10 years	−0.357	0.040	−0.200	0.238	−0.663	0.007
10–20 years	−0.183	0.154	−0.392	0.092	−0.171	0.229
>20 years	−0.227	0.031	−0.211	0.119	−0.371	0.059

*Corrected for the time of disease duration.
†Corrected for age.
BCVA, best Snellen corrected visual acuity; CFT, center foveal thickness; MD, mean deviation; RP, retinitis pigmentosa; USH2, Usher syndrome type IIa.