Demographics of the study population
| Variable | Healthy eyes (n=24) | NTG eyes (n=43) | P value |
| Age, mean (SD; 95% CI), years | 66.2 (6.1; 63.6 to 68.7) | 63.3 (9.8; 60.3 to 66.3) | 0.201* |
| No of men/women | 11/13 | 19/24 | 0.897† |
| VF defect location, no of superior/inferior | – | 27/16 | |
| Spherical equivalent, mean (SD; 95% CI), D | −0.55 (2.13; −1.45 to 0.35) | −1.51 (2.44; −2.26 to–0.76) | 0.112* |
| Axial length, mean (SD; 95% CI), mm | 23.8 (1.1; 23.4 to 24.3) | 24.1 (1.3; 23.7 to 24.5) | 0.324* |
| IOP, mean (SD; 95% CI), mm Hg | 15.7 (3.0; 14.4 to 16.9) | 15.3 (2.5; 14.5 to 16.1) | 0.598* |
| SBP, mean (SD; 95% CI), mm Hg | 131.1 (9.5; 127.1 to 135.1) | 130.3 (9.6; 127.3 to 133.2) | 0.742* |
| DBP, mean (SD; 95% CI), mm Hg | 77.1 (9.6; 73.1 to 81.2) | 78.0 (11.3; 74.5 to 81.5) | 0.744* |
| MOPP, mean (SD; 95% CI), mm Hg | 47.7 (6.0; 45.2 to 50.3) | 48.3 (6.9; 46.2 to 50.5) | 0.726* |
| HR, mean (SD; 95% CI), beats/min | 65.8 (7.6; 62.5 to 69.0) | 65.5 (8.5; 62.9 to 68.1) | 0.892* |
| Hypertension, No. (%) | 5 (21) | 6 (14) | 0.466† |
| SAP MD, mean (SD; 95% CI), dB | 0.48 (1.33; −0.09 to 1.04) | −5.01 (3.83; −6.20 to –3.84) | <0.001* |
| SAP PSD, mean (SD; 95% CI), dB | 1.79 (0.41; 1.62 to 1.96) | 9.88 (4.13; 8.61 to 11.15) | <0.001* |
| Disc area, mean (SD; 95% CI), mm2 | 2.21 (0.43; 2.03 to 2.39) | 2.32 (0.60; 2.13 to 2.50) | 0.449* |
| Rim area, mean (SD; 95% CI), mm2 | 1.15 (0.50; 0.94 to 1.36) | 0.59 (0.30; 0.50 to 0.68) | <0.001* |
Boldface indicates statistically significant difference.
*Calculated as unpaired t-test, with p<0.05 considered to be statistically significant.
†Calculated as χ2 test, with p<0.05 considered to be statistically significant.
dB, decibel; DBP, diastolic blood pressure; HR, heart rate; IOP, intraocular pressure; MD, mean deviation; MOPP, mean ocular perfusion pressure; NTG, normal-tension glaucoma; PSD, pattern SD; SAP, standard automated perimetry; SBP, systolic blood pressure; VF, visual field.