Mean 1-year changes in VA, stratified by antivascular endothelial growth factor injection frequency
Number of injections in 1 year | |||||||||||||
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | |
Patient eyes | |||||||||||||
n | 1908 | 2054 | 2447 | 2512 | 2644 | 2868 | 2943 | 3027 | 2878 | 2380 | 1641 | 1029 | 295 |
% | 7 | 7 | 9 | 9 | 9 | 10 | 10 | 11 | 10 | 8 | 6 | 4 | 1 |
Gender (%) | |||||||||||||
Male | 52 | 53 | 53 | 53 | 54 | 52 | 53 | 52 | 53 | 53 | 53 | 54 | 60 |
Female | 48 | 47 | 47 | 47 | 46 | 48 | 47 | 48 | 47 | 47 | 47 | 46 | 40 |
Mean age (years) | 61.6 | 61.0 | 61.3 | 61.5 | 61.9 | 62.5 | 62.3 | 62.8 | 62.9 | 62.6 | 62.8 | 62.3 | 61.8 |
Mean VA (letters) | |||||||||||||
Baseline VA | 56.1 | 58.9 | 59.7 | 59.9 | 59.5 | 59.5 | 59.9 | 59.2 | 59.6 | 59.1 | 59.3 | 58.7 | 59.7 |
Change at 1 year | +4.3 | +2.2 | +1.5 | +1.8 | +2.7 | +3.6 | +4.2 | +5.4 | +5.8 | +6.8 | +6.5 | +7.5 | +7.8 |
Final VA | 60.4 | 61.1 | 61.1 | 61.7 | 62.3 | 63.1 | 64.2 | 64.6 | 65.4 | 65.9 | 65.9 | 66.1 | 67.5 |
P value | <0.001 | <0.001 | 0.002 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
95% CI | 3.0 to 5.6 | 1.0 to 3.3 | 0.5 to 2.5 | 0.8 to 2.8 | 1.9 to 3.6 | 2.8 to 4.3 | 3.5 to 5.0 | 4.7 to 6.0 | 5.1 to 6.4 | 6.1 to 7.5 | 5.7 to 7.4 | 6.4 to 8.6 | 5.9 to 9.7 |
VA, visual acuity.