Table 1

Distribution of the subjects within groups, characteristics and vascular density

Control groupGroup 1—mild diseaseGroup 2—moderate diseaseGroup 3—severe diseaseSignificance among all groups
GenderMale101210120.520*
Female1712149
Age (years)Mean394142440.333†
DiabetesNo272422190.189*
Yes0022
SmokerNo222124190.186*
Yes5302
RaceCaucasic272319110.001*§
Latin0159
Other0001
ACEI useNo262424200.550*
Yes1001
Days from PCRMean7270
Central VDMean16.9017.1613.3713.630.000†§
SD3.103.484.903.78
Inferior VDMean50.3749.5549.6748.780.827‡
SD3.252.634.884.56
Superior VDMean49.7248.8249.0349.460.733†
SD3.432.992.703.28
Nasal VDMean43.9244.2643.8644.210.970†
SD2.594.412.807.74
Temporal VDMean47.7745.9948.4147.870.020‡§
SD2.203.464.193.97
FAZMean0.250.200.350.310.000‡
SD0.070.080.150.10
Image qualityMean64,9664.1366,8865,950.441‡
SD5,216,614,254,75
  • 2 test.

  • †ANOVA test and Bonferroni correction.

  • ‡Kruskal-Wallis and Mann-Whitney U test.

  • §Statistically significant p<0.05.

  • ACEI, ACE inhibitor; ANOVA, analysis of variance; FAZ, foveal avascular zone; VD, vascular density.