Table 2

Univariate and multivariate risk factors for VF deterioration in patients with POAG and PPA

Variable	Univariate analysis		Multivariate analysis
Variable	HR (95% CI)	P value	HR (95% CI)	P value
Age, per year older	1.001 (0.967 to 1.036)	0.972
Female sex	1.621 (0.778 to 3.376)	0.197
Baseline IOP, per mm Hg	1.028 (0.940 to 1.125)	0.545
Percentage reduction in IOP, per % greater	1.022 (0.993 to 1.052)	0.131
Spherical equivalent, per one diopters greater	1.027 (0.770 to 1.370)	0.855
Central corneal thickness, per μm thinner	1.001 (0.994 to 1.008)	0.738
AXL, per mm greater	1.804 (0.910 to 3.575)	0.091	2.575 (0.997 to 6.649)	0.051
Detection of disc haemorrhage	2.200 (0.944 to 5.132)	0.068	2.661 (1.078 to 6.568)	0.034
Optic disc tilt ratio, per 0.1 greater	0.054 (0.003 to 8.903)	0.81
PPA area, per mm² greater	1.319 (0.473 to 3.681)	0.597
PPA irregularity index >1.23	1.329 (1.037 to 1.704)	0.025	1.455 (1.109 to 1.909)	0.007
Baseline MD, per dB worse	1.045 (0.926 to 1.179)	0.476

P values <0.1 at univariate analysis and <0.05 at multivariate analysis are presented with bold characters.
AXL, axial length; IOP, intraocular pressure; MD, mean deviation; POAG, primary open-angle glaucoma; PPA, parapapillary atrophy.