Table 3

Comparison of mean difference in vessel diameter (µm) measured from two OCTA protocols and AOO

Unit: µmTotal
(n=240)		Arteries
(n=147)		Veins
(n=93)		D≥45 µm
(n=133)		D<45 µm
(n=107)
Mean difference
OCTA3–AOO
(95% CI)
p value		 4.7 (4.0 to 5.4) 4.9 (3.9 to 5.8) 4.4 (3.3 to 5.5) 4.6 (3.5 to 5.7) 4.7 (3.8 to 5.7)
<0.001 <0.001 <0.001 0.001 <0.001
ICC (95% CI)0.94 (0.92 to 0.95)0.91 (0.88 to 0.94)0.96 (0.94 to 0.97)0.90 (0.86 to 0.92)0.68 (0.57 to 0.77)
Mean difference
OCTA9–AOO
(95% CI)
p value		 4.2 (3.5 to 4.9) 4.3 (3.4 to 5.1) 4.1 (3.0 to 5.3) 2.7 (1.7 to 3.7) 6.1 (5.3 to 6.9)
<0.001 <0.001 <0.001 <0.001 <0.001
ICC (95% CI)0.93 (0.92 to 0.95)0.92 (0.89 to 0.94)0.95 (0.92 to 0.96)0.90 (0.87 to 0.93)0.70 (0.59 to 0.79)
Mean difference
OCTA9–OCTA3
(95% CI)
p value		−0.5 (−1.3 to 0.4)−0.6 (−1.8 to 0.5)−0.2 (−1.6 to 1.1)−1.9 (−3.2 to −0.6) 1.3 (0.3 to 2.3)
0.2980.3010.729 0.005 0.009
ICC (95% CI)0.90 (0.87 to 0.92)0.87 (0.82 to 0.90)0.93 (0.89 to 0.95)0.84 (0.78 to 0.88)0.66 (0.54 to 0.76)

  • p < 0.05 for values in bold

  • AOO, adaptive optics ophthalmoscope; ICC, intraclass correlation coefficient; OCTA, optical coherence tomography angiography.