Table 2

Univariable analysis of recipient, donor and surgery parameters for undergoing rebubbling after DMEK surgery

All consecutive performed DMEK (n=752)
Rebubbling rate (n=144) (%)OR95% CIP value
Recipient parameters
Age, years1.03 (per 1 unit)1.01 to 1.050.005
Sex1.020.71 to 1.470.91
 Male19
 Female19
Baseline IOP, mm Hg1.00 (per 1 unit)0.95 to 1.060.97
Baseline CCT, µm1.00 (per 1 unit)0.99 to 1.000.62
Indication, FED1.80.87 to 3.700.11
 Yes20
 No12
Indication, PBK1.210.39 to 3.740.74
 Yes22
 No19
Indication, graft failure0.650.25 to 1.700.34
 Yes13
 No19
Lens status, PPC1.120.75 to 1.820.49
 Yes20
 No17
Ocular comorbidities, except cataract0.740.40 to 1.30.29
 Yes15
 No20
Donor parameters
Age, years1.00 (per 1 unit)0.97 to 1.020.76
Sex0.880.60 to 1.280.5
 Male18
 Female20
Graft diameter, mm
 <8.517
 8.5191.160.67 to 2.010.59
 >8.5302.130.98 to 4.610.06
ECD, cells/mm21.00 (per 1 unit)0.99 to 1.000.61
Complicated graft preparation1.530.54 to 4.310.42
 Yes26
 No19
Surgery parameters
Surgical complication21.13 to 3.540.016
 Yes31
 No18
Diameter descemetorhexis, mm
 <8.524to
 8.5190.730.44 to 1.190.2
 >8.5180.680.42 to 1.110.12
Recipient donor sex mismatch1.050.73 to 1.520.78
 Yes20
 No19
Surgery date after 20151.770.96 to 3.270.06
 Yes20
 No12
Triple procedure0.890.43 to 1.890.78
 Yes18
 No19
Phakic DMEK0.860.39 to 1.880.7
 Yes17
 No19
PPC vs phakic DMEK1.190.54 to 2.630.66
PPC vs triple DMEK1.140.54 to 2.420.72
PPC and triple DMEK vs phakic DMEK1.180.54 to 2.590.68
Eye undergoing surgery0.720.49 to 1.030.07
 Left16
 Right22
  • BCVA, best-corrected visual acuity; CCT, central cornea thickness; DMEK, Descemet membrane endothelial keratoplasty; ECD, endothelial cell density; FED, Fuchs endothelial dystrophy; IOP, intraocular pressure; PBK, pseudophakic bullous keratopathy; PPC, pseudophakic, posterior chamber.