Table 3

Comparisons of baseline and follow-up data between low and high MSGFR groups

Low MSGFR groupHigh MSGFR groupP value
Baseline
 Number of eyes108
 Age33 (24.5–40.5) years31.5 (24–43.75) years0.897
 Sex5 males, 5 females2 males, 6 females0.367
 Sides6 right eyes, 4 left eyes5 right eyes, 3 left eyes1.0
 Aetiology9 SJSs, 1 GVHDs6 SJSs, 2 GVHDs0.537
 Medical history15 (6–23) years5 (4.25–10.5) years0.101
 Donors sizes8 (6.49–11.41) cm28.13 (6.88–10.18) cm20.829
 Schirmer test0 (0–0) mm0 (0–2.75) mm0.315
 FL12 (9–12)12 (12–12)0.315
 TBUT0 (0–0) s0 (0–0) s1.0
 BCVA0.05 (0.01–0.45)0.09 (0.05–0.10)0.173
3 months follow-up
 Number of eyes108
 Schirmer test1 (0.5–4) mm5 (4–6) mm0.012
 FL10 (9–12)10 (8.5–10)0.315
 TBUT0 (0–0) s0 (0–0) s0.696
 BCVA0.02 (0.01–0.44)0.15 (0.06–0.4)0.068
Long-term follow-up
 Number of eyes9*8
 Follow-up time3 (3–4.5) years4.5 (2.25–6) years0.573
 Schirmer test1 (0–5) mm5 (4–7) mm0.027
 FL8 (8–12)10 (6.5–11.5)0.673
 TBUT0 (0–0)0 (0–0)1.0
 BCVA0.05 (0.01–0.43)0.19 (0.1–0.4)0.139
  • Continuous variables were shown as median (IQR).

  • *One eye was lost to follow-up after 3 months.

  • BCVA, best-corrected visual acuity; DED, dry eye disease; FL, corneal fluorescein staining score; GVHD, graft versus host disease; MSGFR, salivary flow rate of minor salivary glands; SJS, Stevens–Johnson syndrome; TBUT, value of break-up time of tear-film.