Table 1

Retinal layer thickness in patients with CHM and healthy controls

Retinal layer thickness
CHM apparently preserved retinal islet
EZ-RPE* ONL* OPL INL* IPL* GCL* RETINA* CHOROID*
44.58±5.1370.63±12.7940.25±7.3037.17±9.7837.38±9.5949.54±9.70286.50±31.51155.67±46.74
p<0.001p<0.001p>0.05p<0.001p<0.001p<0.001p<0.001p<0.001
CHM atrophic retina
EZ-RPE* ONL* OPL* INL* IPL* GCL* RETINA* CHOROID*
21.96±3.3837.67±14.3230±9.7336.75±9.0537.71±7.9340.75±9.97217.88±36.8775.96±34.05
p<0.001p<0.001p<0.001p<0.001p<0.001p<0.001p<0.001p<0.001
Healthy controls
EZ-RPE ONL OPL INL IPL GCL RETINA CHOROID
72.81±5.5592.13±7.2441.13±5.8945.94±6.3347.75±7.0661.86±7.39398.24±18.57286.86±91.15
  • All values are expressed in μm (mean±SD).

  • *Statistically significant changes compared with controls.

  • CHM, choroideremia; EZ-RPE, ellipsoid zone–retinal pigment epithelium layer; GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; ONL, outer nuclear layer; OPL, outer plexiform layer.