Retinal layer thickness | |||||||
---|---|---|---|---|---|---|---|
CHM apparently preserved retinal islet | |||||||
EZ-RPE* | ONL* | OPL | INL* | IPL* | GCL* | RETINA* | CHOROID* |
44.58±5.13 | 70.63±12.79 | 40.25±7.30 | 37.17±9.78 | 37.38±9.59 | 49.54±9.70 | 286.50±31.51 | 155.67±46.74 |
p<0.001 | p<0.001 | p>0.05 | p<0.001 | p<0.001 | p<0.001 | p<0.001 | p<0.001 |
CHM atrophic retina | |||||||
EZ-RPE* | ONL* | OPL* | INL* | IPL* | GCL* | RETINA* | CHOROID* |
21.96±3.38 | 37.67±14.32 | 30±9.73 | 36.75±9.05 | 37.71±7.93 | 40.75±9.97 | 217.88±36.87 | 75.96±34.05 |
p<0.001 | p<0.001 | p<0.001 | p<0.001 | p<0.001 | p<0.001 | p<0.001 | p<0.001 |
Healthy controls | |||||||
EZ-RPE | ONL | OPL | INL | IPL | GCL | RETINA | CHOROID |
72.81±5.55 | 92.13±7.24 | 41.13±5.89 | 45.94±6.33 | 47.75±7.06 | 61.86±7.39 | 398.24±18.57 | 286.86±91.15 |
All values are expressed in μm (mean±SD).
*Statistically significant changes compared with controls.
CHM, choroideremia; EZ-RPE, ellipsoid zone–retinal pigment epithelium layer; GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; ONL, outer nuclear layer; OPL, outer plexiform layer.