Table 3

pRNFL thickness change versus group control in the four quadrants and the 360° average

Group1st group (within 3 months)2nd group (3–6 months)3rd group (6–9 months)4th group (9–12 months)5th group (12–24 months)6th group (24–60 months)7th group (>60 months)
RNFL average thickness change versus group control6.61%−17.78%*−37.63%*−50.18%−51.35%−61.37%−57.23%
RNFL S thickness change versus group control12.15%−12.58%*−30.36%−47.81%*−46.44%−62.25%*−53.39%
RNFL N thickness change versus group control26.13%*−2.44%−17.66%−34.57%−38.22%−50.84%−51.11%
RNFL I thickness change versus group control10.37%−11.72%−40.28%*−47.79%−52.72%−62.89%−57.69%
RNFL T thickness change versus group control−20.92%*−44.37%*−57.58%−67.20%−61.71%−64.77%−66.34%
  • *P<0.05 when compared with the former group.

  • Date are shown as % change versus group control. Values were compared by one-way analysis of covariance, followed by Bonferroni posthoc test. Sex and age were used as covariates in the analysis.

  • Group control, healthy control; I, inferior; N, nasal; RNFL, retinal nerve fibre layer; S, superior; T, temporal; 1st group, disease duration ≤3 months; 2nd group, disease duration 3–6 months; 3rd group, disease duration 6–9 months; 4th group, disease duration 9–12 months; 5th group, disease duration 12–24 months; 6th group, disease duration 24–60 months; 7th group: disease duration >60 months.