Association between change in the FAZ area and ocular variables: univariate and multivariable analyses (n=108 eyes)
| Change in the FAZ area, mm2 | ||||||
|---|---|---|---|---|---|---|
| Univariate model | Multivariate model 1 | Multivariate model 2 | ||||
| Variables | Coefficients | P value | Coefficients | P value | Coefficients | P value |
| (95% CI) | (95% CI) | (95% CI) | ||||
| Age (years) per 10 years | −0.002 (−0.010 to 0.007) | 0.667 | 0.006 (−0.026 to 0.038) | 0.154 | −0.005 (−0.013 to 0.003) | 0.244 |
| Gender (male/female) | 0.000 (−0.019 to 0.020) | 0.855 | ||||
| CCT (μm) per 100 μm | 0.043 (0.015 to 0.071) | 0.004* | 0.113 (−0.013 to 0.214) | 0.103 | −0.021 (−0.005 to 0.047) | 0.108 |
| Axial length (mm) per 1 mm | −0.002 (−0.008 to 0.004) | 0.523 | ||||
| Foveal sensitivity (1/Lumbert) per 1000 units | −0.011 (0.015 to −0.007) | <0.001* | −0.022 (−0039 to −0.005) | 0.010** | −0.005 (−0.010 to −0.001) | 0.018** |
| Preoperative FAZ area (mm2) per mm2 | −0.158 (−0.207 to −0.109) | <0.001* | −0.111 (−0.166 to −0.055) | <0.001** | −0.137 (−0.192 to −0.083) | <0.001** |
| Change in IOP (mmHg) per 10 mmHg | −0.017 (−0.026 to −0.007) | 0.001* | −0.010 (−0.019 to −0.002) | 0.013** | ||
| Surgery | ||||||
| Glaucoma surgery alone (yes/no) | −0.033 (−0.052 to −0.014) | 0.001* | −0.022 (−0.039 to −0.004) | 0.016** | ||
| Glaucoma surgery combined with cataract surgery (yes/no) | −0.046 (−0.063 to −0.029) | <0.001* | −0.031 (−0.047 to −0.014) | <0.001** | ||
*p<0.10, univariate analysis.
**p<0.05, multivariate analysis.
IOP, intraocular pressure; CCT, central corneal thickness; FAZ, foveal avascular zone; OCTA, optical coherence tomography angiography; PG, prostaglandin.