Demographics and ocular characteristics of the study population
| Surgery group | Non-surgery group | P value | |
|---|---|---|---|
| Patients (n) | 54 | ||
| Age (years) | 66.7±11.3 | ||
| Gender (male/female) | 25/29 | ||
| Eyes (n) | 54 | 54 | |
| BCVA (LogMAR) | 0.09 (−0.08, 0.24) | 0.00 (−0.08, 0.09) | 0.047 |
| CCT (μm) | 506±35 | 512±32 | 0.061 |
| Axial length (mm) | 24.9±1.7 | 24.9±1.7 | 0.932 |
| Preoperative IOP (mmHg) | 22.1±9.5 | 16.9±4.4 | <0.001 |
| Postoperative IOP (mmHg) | 10.3±3.5 | 16.5±3.5 | <0.001 |
| HFA 24-2 MD (dB) | −17.4 (−24.5, −11.0) | −8.5 (−16.1, −1.7) | <0.001 |
| Central-4-point mean sensitivity (dB) | 24.2 (18.2, 27.0) | 30.8 (27.2, 33.7) | <0.001 |
| Foveal sensitivity (dB) | 32.0 (29.0, 35.0) | 35.0 (30.0, 36.25) | 0.072 |
| Preoperative image score | 9.1±0.7 | 9.1±0.7 | 0.727 |
| Postoperative image score | 9.0±0.7 | 9.2±0.6 | 0.077 |
| Preoperative vessel density (%) | 41.4±5.0 | 42.3±5.8 | 0.157 |
| Combined cataract surgery, n (%) | 31 (57.4) | n.a. | |
| Type of glaucoma surgery, n (%) | n.a. | ||
| Ab interno trabeculotomy | 12 (22.2) | ||
| Filtering surgery | 40 (74.1) | ||
| Tube shunt (Ahmed glaucoma valve) | 2 (3.7) | ||
| Medications | |||
| Preoperative β-blocker, n (%) | 44 (81.5) | 35 (64.8) | <0.001 |
| Preoperative PG analogue, n (%) | 51 (94.4) | 39 (72.2) | <0.001 |
| Postoperative β-blocker, n (%) | 8 (14.8) | 28 (51.8) | <0.001 |
| Postoperative PG analogue, n (%) | 9 (16.7) | 30 (55.6) | <0.001 |
For normally distributed variables, results are shown as mean±SD; for non-normally distributed variables, results are shown as median (IQR). Data expressed as mean±SD were compared with paired t-test. Data expressed as the median (IQR) were compared using the non-parametric Wilcoxon signed-rank test. McNemar’s test was used to compare the frequencies of medication use between surgery group and non-surgery group.
BCVA, best correlated visual acuity; CCT, central corneal thickness; HFA, Humphrey field analyser; IOL, intraocular lens; IOP, intraocular pressure; LogMAR, logarithm of the minimum angle of resolution; MD, mean deviation; n.a, not applicable; PG, prostaglandin; SE, spherical equivalent.