Clinical information of recipients of viral DNA positive-grafts
| No. | Age range | Sex | Clinical diagnosis | Type of transplantation | BCVA | IOP (mm Hg) | Viral DNA | ECD of donor (cells/mm2) | Last time of follow-up | ECD of graft at postoperative follow-up (cells/mm2) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BCVA | IOP (mm Hg) | CCT (μm) | 6 | 12 | 24 | |||||||||
| 1 | 40s | M | Pseudophakic bullous keratopathy | DSAEK | 2.3 | 8.0 | HSV-1 (+) | 4735 | 0.1 | 10.3 | 525 | 3045 | 2716 | 1845 |
| 6 | 30s | M | Ocular trauma | DSAEK | 2.3 | 30.0 | HSV-1 (+) | 3077 | 1.0 | 23.4 | 600 | 1982 | 1859 | 1232 |
| 11 | 70s | F | Fuchs endothelial dystrophy | DSAEK | 0.4 | 11.6 | HSV-1 (+) | 2722 | 0.1 | 19.0 | 624 | 2350 | 2005 | 1316 |
| 22 | 80s | F | Bullous keratopathy due to PHACO | DMEK | 1.1 | 10.0 | HSV-1 (+) | 3189* | 0.5 | 15.1 | 547 | 1732 | 1656 | – |
| 24 | 50s | M | Bullous keratopathy due to PHACO | DSAEK | 2.3 | 16.0 | HSV-1 (+) | 3016* | 0.3 | 17.5 | 912 | 1302 | 1298 | – |
| 8 | 30s | M | Alkaline burn of ocular surface | PK | 2.3 | 10.0 | HSV-1 (+) | 3945 | 2.3 | 12.0 | 680 | 2120 | 1958 | 1458 |
| 12 | 20s | M | Keratoconus | DALK | 2.0 | 6.0 | HSV-1 (+) | – | 0.0 | 9.9 | 500 | 1754 | 1703 | 1632 |
| 21 | <3years | F | Congenital glaucoma | DALK | 2.6 | 24.0 | HSV-1 (+) | – | 2.3 | 21.5 | 490 | 2698 | 2585 | 2415 |
| 23 | 10s | M | Keratoconus | DALK | 2.0 | 7.0 | HSV-1 (+) | – | 0.1 | 13.0 | 525 | 3153 | 3089 | 2989 |
| 25 | 10s | M | Keratoconus | DALK | 2.0 | 7.0 | HSV-1 (+) | – | 0.0 | 13.8 | 640 | 2856 | 2783 | 2603 |
| 9 | 30s | F | Congenital corneal leucoplakia | DSAEK | 2.3 | 20.0 | CMV (+) | 3530 | 0.7 | 18.7 | 1050 | 1456 | 1234 | 994 |
| 18 | 20s | M | Congenital corneal leucoplakia | DSAEK | 2.3 | 14.0 | CMV (+) | 3930 | 0.5 | 10.0 | 579 | 1842 | 1621 | 1556 |
| 2 | <1 year | F | Congenital corneal leucoplakia | PK | 2.6 | 26.3 | CMV (+) | 3130 | 0.5 | 15.6 | 558 | 2350 | 2023 | 1182 |
| 10 | 30s | M | Thermal burn of ocular surface | PK | 2.3 | 9.0 | CMV (+) | 3764 | 0.3 | 10.2 | 561 | 2139 | 1898 | 1587 |
| 13 | 50s | M | Alkaline burn of ocular surface | PK | 2.3 | 6.0 | CMV (+) | 2788 | 2.0 | 14.5 | 509 | 2457 | 1958 | 1297 |
| 17 | 30s | M | Bullous keratopathy due to PPV | PK | 2.3 | 12.0 | CMV (+) | 3378 | 0.5 | 18.0 | 588 | 2165 | 1795 | 1818 |
| 20 | 70s | M | Alkaline burn of ocular surface | PK | 2.3 | 6.6 | CMV (+) | 3332 | 2.0 | 9.8 | 598 | 2385 | 2047 | 1967 |
| 19 | 80s | F | Scleral melting | DALK | 0.4 | 13.0 | CMV (+) | – | 0.4 | 11.0 | 519 | 2109 | 2045 | 1983 |
| 24 | 50s | F | Corneal leucoplakia | DALK | 1.0 | 11.0 | CMV (+) | – | 0.3 | 14.5 | 527 | 1699 | 1602 | 1605 |
| 4 | 50s | M | Prior DSAEK failure | DSAEK | 1.4 | 22.0 | VZV (+) | 2986 | 0.5 | 20.3 | 738 | 2006 | 1656 | 1433 |
| 14 | <1 year | M | Congenital endothelial dystrophy | DSAEK | 2.6 | 9.0 | VZV (+) | 3547 | 0.7 | 16.0 | 605 | 2848 | 2222 | 2031 |
| 3 | 60s | M | Fungal keratitis | PK | 2.0 | 13.0 | VZV (+) | 2758 | 0.3 | 18.6 | 503 | 1301 | 1003 | 983 |
| 5 | <1 year | M | Peter anomaly | PK | 2.6 | 26.5 | VZV (+) | 3545 | 0.5 | 13.4 | 533 | 2421 | 2569 | 1403 |
| 7 | 20s | M | Fungal keratitis after trauma | PK | 2.3 | 9.0 | VZV (+) | 3539 | 0.5 | 12.8 | 810 | 2753 | 2525 | 1285 |
| 15 | 70s | F | Corneal marginal degeneration | DALK | 0.8 | 12.0 | VZV (+) | – | 0.7 | 12.0 | 590 | 1867 | 1800 | 1756 |
| 16 | 20s | M | Bullous keratopathy due to glaucoma | DSAEK | 2.0 | 21.0 | EBV (+) | 3845 | 0.3 | 20.0 | 686 | 2710 | 2321 | 2292 |
| 25 | <1 year | M | Congenital glaucoma | DSAEK | 2.6 | 11.0 | EBV (+) | 3212 | 1.0 | 15.0 | 598 | 2789 | 2598 | 1732 |
BCVA, best-corrected visual acuity; CCT, central corneal thickness; CMV, cytomegalovirus; DSAEK, descemet stripping automated endothelium keratoplasty; DMEK, descemet membrane endothelial keratoplasty; DALK, deep lamellar keratoplasty; ECD, endothelial cell density; HSV, herpes simplex virus; IOP, intraocular pressure; PK, penetrating keratoplasty; PPV, pars plana vitrectomy; VZV, varicella-zoster virus.
*The ECD of the donor was measured a second time.