Table 2

Comparison of thicknesses of retinal layers at baseline and safety visit (p values, paired t-test): significant values (p<0.05)

Layers	P value comparing thickness at baseline and safety visit (paired t-test)
	Central measures		Superior ETDRS subfields		Temporal ETDRS subfields		Inferior ETDRS subfields		Nasal ETDRS subfields
	Central point	Central mm subfield	Inner	Outer	Inner	Outer	Inner	Outer	Inner	Outer
Entire retina (ILM to RPE)	0.008	0.015	0.299	0.346	0.187	0.378	0.027	0.043	0.048	0.117
Nerve fibre layer (ILM to outer border of NFL)	0.048	0.029	0.014	0.214	0.110	0.107	0.193	0.265	0.069	0.025
GCL-IPL-INL layer (outer border NFL to outer border INL)	0.932	0.801	0.627	0.999	0.409	0.572	0.020	0.026	0.251	0.587
OPL-ONL-ELM-IS layer (outer border INL to IS–OS line)	0.522	0.967	0.559	0.297	0.877	0.480	0.539	0.409	0.648	0.857
Outer retina (IS–OS line to RPE)	0.014	0.007	0.108	0.127	0.086	0.127	0.060	0.089	0.078	0.170

GCL, ganglion cell layer; ILM, inner limiting membrane; INL, inner nuclear layer; IPL, inner plexiform layer; IS-OS, inner-outer segment junction ; IS–OS, inner–outer segment; NFL, nerve fibre layer; ONL, outer nuclear layer; RPE, retinal pigment epithelium.