Table 2

Percent suppression of rod b-wave amplitude recovery rate prebleaching and 30 min postbleaching at month 1, relative to baseline*

Percent suppressionEmixustat 2.5 mg
(N=6)
Emixustat 5 mg
(N=7)
Emixustat 10 mg
(N=6)
at month 1PrebleachPostbleachPrebleachPostbleachPrebleachPostbleach
n667766
Mean (SD)−18.85 (47.02)−3.31 (41.43)4.19 (22.12)52.20 (34.99)49.98 (41.52)91.86 (13.63)
SE19.2016.918.3613.2216.955.56
Median−11.03−12.23−3.0768.0049.0496.69
Minimum, maximum−80.7 to 37.5−41.0 to 54.7−22.8 to 35.31.0 to 91.54.3 to 100.064.9 to 100.0
  • *A positive percent suppression indicates a decrease from baseline and a negative percent suppression indicates an increase from baseline.