Baseline and follow-up data of the eyes
| Baseline | Long-term follow-up | |
| General information | ||
| Number of eyes | 18 | – |
| Sex | 11 females, 7 males | – |
| Age | 31 (range: 23–56) years | – |
| Aetiology | 15 SJSs, 3 GVHDs | – |
| Medical history | 6 (range: 0.7–33) years | – |
| Data of grafts | ||
| Donor sites | 12 low lips, 5 upper lips, 1 buccal mucosa | – |
| Sizes | 8.1 (range: 5.8–15) cm2 | – |
| MSGFR | 1.7 (range: 0.9–3.3) µL/min/cm2 | – |
| Patients questionnaire | ||
| Follow-up time | – | 6 (range: 4–8) years |
| Number of eyes | – | 18 |
| Relief of DED symptoms | – | 58.8%* |
| Satisfaction rate | – | 70.6%* |
| Ophthalmological evaluations | ||
| Follow-up time | – | 3.5 (range: 2–8) years |
| Number of eyes | – | 17† |
| Schirmer test | 0 (IQR: 0–0.5) mm | 4 (IQR: 1–7) mm‡ |
| FL | 12 (IQR: 10–12) | 10 (IQR: 8–12)‡ |
| TBUT | 0 s | 0 s in 15 eyes, 2 s in two eyes |
| BCVA | 0.05 (IQR: 0.01–0.1) | 0.05 (IQR: 0.02–0.33) |
*Only the right eye was included in the patient undergoing bilateral surgeries.
†The ophthalmological examinations of the eye lost to follow-up after 3 months were not included in the analysis.
‡P §amp;lt; 0.05.
BCVA, best-corrected visual acuity; DED, dry eye disease; FL, corneal fluorescein staining score; GVHD, graft versus host disease; MSGFR, salivary flow rate of minor salivary glands; SJS, Stevens-Johnson syndrome; TBUT, value of break-up time of tear-film.