Comparisons of baseline and follow-up data between low and high MSGFR groups
| Low MSGFR group | High MSGFR group | P value | |
| Baseline | |||
| Number of eyes | 10 | 8 | |
| Age | 33 (24.5–40.5) years | 31.5 (24–43.75) years | 0.897 |
| Sex | 5 males, 5 females | 2 males, 6 females | 0.367 |
| Sides | 6 right eyes, 4 left eyes | 5 right eyes, 3 left eyes | 1.0 |
| Aetiology | 9 SJSs, 1 GVHDs | 6 SJSs, 2 GVHDs | 0.537 |
| Medical history | 15 (6–23) years | 5 (4.25–10.5) years | 0.101 |
| Donors sizes | 8 (6.49–11.41) cm2 | 8.13 (6.88–10.18) cm2 | 0.829 |
| Schirmer test | 0 (0–0) mm | 0 (0–2.75) mm | 0.315 |
| FL | 12 (9–12) | 12 (12–12) | 0.315 |
| TBUT | 0 (0–0) s | 0 (0–0) s | 1.0 |
| BCVA | 0.05 (0.01–0.45) | 0.09 (0.05–0.10) | 0.173 |
| 3 months follow-up | |||
| Number of eyes | 10 | 8 | |
| Schirmer test | 1 (0.5–4) mm | 5 (4–6) mm | 0.012 |
| FL | 10 (9–12) | 10 (8.5–10) | 0.315 |
| TBUT | 0 (0–0) s | 0 (0–0) s | 0.696 |
| BCVA | 0.02 (0.01–0.44) | 0.15 (0.06–0.4) | 0.068 |
| Long-term follow-up | |||
| Number of eyes | 9* | 8 | |
| Follow-up time | 3 (3–4.5) years | 4.5 (2.25–6) years | 0.573 |
| Schirmer test | 1 (0–5) mm | 5 (4–7) mm | 0.027 |
| FL | 8 (8–12) | 10 (6.5–11.5) | 0.673 |
| TBUT | 0 (0–0) | 0 (0–0) | 1.0 |
| BCVA | 0.05 (0.01–0.43) | 0.19 (0.1–0.4) | 0.139 |
Continuous variables were shown as median (IQR).
*One eye was lost to follow-up after 3 months.
BCVA, best-corrected visual acuity; DED, dry eye disease; FL, corneal fluorescein staining score; GVHD, graft versus host disease; MSGFR, salivary flow rate of minor salivary glands; SJS, Stevens–Johnson syndrome; TBUT, value of break-up time of tear-film.