Summary of reports on macular thickness measurements in healthy subjects using different spectral domain-OCT device
| Study | Country | Year | SD-OCT system | Mean age±SD | Number of eyes/subjects searched | Central macular thickness (mean μm±SD) | Foveal macular volume (mm3) | Total macular volume (mm3) | Repeatability of full-retinal layer thickness (ICC, 95% CI) |
| Hanno et al22 | Norway | 2007–2008 | Cirrus HD-OCT (Carl Zeiss Meditec) | 61.0±8.0 | 7686/4508 | 265.9±21.4 | NA | 8.02±0.36 | NA |
| Hashemi et al23 | Iran | 2008–2009 | Cirrus HD-OCT (Carl Zeiss Meditec) | 54.2±5.6 | 3024/3024 | 255.4±23.8 | NA | 10.01±0.51 | NA |
| Song et al14 | Korea | 2008–2009 | Cirrus HD-OCT (Carl Zeiss Meditec) | 55.6±16.4 | 198/198 | 253.9±24.2 | NA | 9.74±0.71 | NA |
| Myers et al24 | United States | 2008–2010 | Topcon 3D OCT-1000 Mark II | 72.6±6.3 | 1838/977 | 287.5±27.0 | NA | NA | NA |
| Adhi et al3 | Pakistan | 2009–2010 | Topcon 3D OCT-1000 Mark II | 45.3 | 220/220 | 229.0±20.5 | NA | NA | NA |
| Patel et al17 | United Kingdom | 2009–2010 | Topcon 3D OCT-1000 Mark II | 55.2±8.2 | 32062/32062 | 264.5±22.9 | NA | 7.87±0.37 | NA |
| Gupta et al11 | China | 2009–2011 | Cirrus HD-OCT (Carl Zeiss Meditec) | 53.2±6.1 | 490/490 | 250.4±20.6 | NA | 10.09±0.41 | NA |
| Chua et al25 | China, Malaysia and India | 2009–2011 | Cirrus SD-OCT (Carl Zeiss Meditec) | 56.0±8.0 | 3043/2047 | 251.8±24.8 | NA | NA | NA |
| Ooto et al26 | Japan | 2010 | 3D-OCT 1000 | 48.6 | 248/248 | 221.9±18.8 | NA | NA | NA |
| Choovuthayakorn et al27 | Thailand | 2011 | Spectralis (Heidelberg Engineering) | 49.2±17.2 | 368/368 | 259.2±19.1 | 0.20±0.02 | 8.59±0.37 | NA |
| Wang et al28 | China | 2011 | Spectralis (Heidelberg Engineering) | 60.0±8.0 | 384/384 | 259.8±18.9 | NA | NA | NA |
| Pokharel et al29 | Nepal | 2013 | Spectralis (Heidelberg Engineering) | 21.2±6.8 | 126/63 | 247.7±19.9 | 0.20±0.02 | 8.49±0.31 | NA |
| Natung et al30 | India | 2013–2014 | Cirrus HD-OCT (Carl Zeiss Meditec) | 38.1±12.1 | 800/400 | 240.4±18.3 | NA | NA | NA |
| Al-Zamil et al31 | Saudi | 2015 | Cirrus HD-OCT (Carl Zeiss Meditec) | 29.9±7.85 | 158/158 | 244.8±23.6 | 0.20±0.02 | 8.48±0.35 | NA |
| Invernizzi et al32 | Italy | 2017 | Spectralis (Heidelberg Engineering) | 39.9±13.9 | 200/200 | 280.1±17.5 | NA | NA | 0.995 |
ICC, intraclass correlation coefficient; OCT, optical coherence tomography.