Patients’ characteristics
| Variables | Development set | Evaluation set | ||||
| FUS group | Control group | P value | FUS group | Control group | P value | |
| Number | 593 | 625 | 377 | 503 | ||
| Mean age at disease onset (SD) (range), years | 32.3 (11.3) (8–70) | 37.9 (14.9) (3–79) | <0.01 | 34.6 (12.8) (3–84) | 41.2 (16.0) (5–86) | <0.01 |
| Mean disease duration (SD) (max), years | 3.8 (5.5) (37) | 3.2 (5.9) (48) | 0.10 | 3.9 (6.5) (35) | 3.1 (6.3) (50) | 0.10 |
| Male, No. (%) | 270 (45.5) | 288 (46.1) | 0.85 | 199 (52.8) | 245 (48.7) | 0.23 |
| Han ethnicity, No. (%) | 573 (96.6) | 602 (96.3) | 0.77 | 357 (94.7) | 486 (96.6) | 0.16 |
| Blurred vision (%) | 344 (58.0) | 300 (48.0) | <0.01 | 237 (62.9) | 259 (51.5) | <0.01 |
| Decreased vision (%) | 328 (55.3) | 407 (65.1) | <0.01 | 181 (48.0) | 316 (62.8) | <0.01 |
| Floaters (%) | 281 (47.4) | 177 (28.3) | <0.01 | 133 (35.3) | 115 (22.9) | <0.01 |
| Eye pain (%) | 198 (33.4) | 316 (50.6) | <0.01 | 144 (38.2) | 256 (50.9) | <0.01 |
| Redness (%) | 171 (28.8) | 395 (63.2) | <0.01 | 108 (28.6) | 287 (57.1) | <0.01 |
| Photophobia (%) | 153 (25.8) | 247 (39.5) | <0.01 | 90 (23.9) | 194 (38.6) | <0.01 |
| Tears (%) | 105 (17.7) | 180 (28.8) | <0.01 | 51 (13.5) | 134 (26.6) | <0.01 |
| Distorted vision (%) | 9 (1.5) | 56 (9.0) | <0.01 | 11 (2.9) | 41 (8.2) | <0.01 |
| Unilateral involvement (%) | 549 (92.6) | 308 (49.3) | <0.01 | 345 (91.5) | 278 (55.3) | <0.01 |
| Mild inflammation in the anterior chamber at presentation (%) | 583 (98.3) | 252 (40.3) | <0.01 | 364 (96.6) | 195 (38.8) | <0.01 |
| Stellate or medium-sized keratic precipitates (%) | 544 (91.7) | 77 (12.3)* | <0.01 | 347 (92.0) | 73 (14.5)* | <0.01 |
| Anterior chamber flare (%) | 534 (90.1) | 392 (62.7) | <0.01 | 332 (88.1) | 304 (60.4) | <0.01 |
| Cells in the anterior chamber (%) | 100 (16.9) | 213 (34.1) | <0.01 | 64 (17.0) | 146 (29.0) | <0.01 |
| Diffuse iris depigmentation (%) | 593 (100.0) | 27 (4.3)† | <0.01 | 377 (100.0) | 14 (2.8)† | <0.01 |
| Absence of posterior synechiae (%) | 593 (100.0) | 411 (65.8) | <0.01 | 377 (100.0) | 348 (69.2) | <0.01 |
| Elevated intraocular pressure (%) | 222 (37.4) | 237 (37.9) | 0.86 | 132 (35.0) | 207 (41.2) | 0.06 |
| Iris nodules (%) | 69 (11.6) | 13 (2.1) | <0.01 | 39 (10.3) | 12 (2.4) | <0.01 |
| Cataract (%) | 429 (72.3) | 164 (26.2) | <0.01 | 253 (67.1) | 126 (25.0) | <0.01 |
| Vitreous opacities (%) | 315 (53.1) | 113 (18.1) | <0.01 | 167 (44.3) | 84 (16.7) | <0.01 |
*Medium-sized keratic precipitates are usually observed in Posner-Schlossman syndrome, and occasionally found in Vogt-Koyanagi-Harada, idiopathic chronic anterior uveitis and presumed virus anterior uveitis.
†Diffuse iris depigmentation with uneven appearance is observed in Posner-Schlossman syndrome.
FUS, Fuchs’ uveitis syndrome.