Table 2

Univariable analysis of recipient, donor and surgery parameters for undergoing rebubbling after DMEK surgery

	All consecutive performed DMEK (n=752)
	Rebubbling rate (n=144) (%)	OR	95% CI	P value
Recipient parameters
Age, years		1.03 (per 1 unit)	1.01 to 1.05	0.005
Sex		1.02	0.71 to 1.47	0.91
Male	19
Female	19
Baseline IOP, mm Hg		1.00 (per 1 unit)	0.95 to 1.06	0.97
Baseline CCT, µm		1.00 (per 1 unit)	0.99 to 1.00	0.62
Indication, FED		1.8	0.87 to 3.70	0.11
Yes	20
No	12
Indication, PBK		1.21	0.39 to 3.74	0.74
Yes	22
No	19
Indication, graft failure		0.65	0.25 to 1.70	0.34
Yes	13
No	19
Lens status, PPC		1.12	0.75 to 1.82	0.49
Yes	20
No	17
Ocular comorbidities, except cataract		0.74	0.40 to 1.3	0.29
Yes	15
No	20
Donor parameters
Age, years		1.00 (per 1 unit)	0.97 to 1.02	0.76
Sex		0.88	0.60 to 1.28	0.5
Male	18
Female	20
Graft diameter, mm
<8.5	17	–	–	–
8.5	19	1.16	0.67 to 2.01	0.59
>8.5	30	2.13	0.98 to 4.61	0.06
ECD, cells/mm²		1.00 (per 1 unit)	0.99 to 1.00	0.61
Complicated graft preparation		1.53	0.54 to 4.31	0.42
Yes	26
No	19
Surgery parameters
Surgical complication		2	1.13 to 3.54	0.016
Yes	31
No	18
Diameter descemetorhexis, mm
<8.5	24	–	to	–
8.5	19	0.73	0.44 to 1.19	0.2
>8.5	18	0.68	0.42 to 1.11	0.12
Recipient donor sex mismatch		1.05	0.73 to 1.52	0.78
Yes	20
No	19
Surgery date after 2015		1.77	0.96 to 3.27	0.06
Yes	20
No	12
Triple procedure		0.89	0.43 to 1.89	0.78
Yes	18
No	19
Phakic DMEK		0.86	0.39 to 1.88	0.7
Yes	17
No	19
PPC vs phakic DMEK		1.19	0.54 to 2.63	0.66
PPC vs triple DMEK		1.14	0.54 to 2.42	0.72
PPC and triple DMEK vs phakic DMEK		1.18	0.54 to 2.59	0.68
Eye undergoing surgery		0.72	0.49 to 1.03	0.07
Left	16
Right	22

BCVA, best-corrected visual acuity; CCT, central cornea thickness; DMEK, Descemet membrane endothelial keratoplasty; ECD, endothelial cell density; FED, Fuchs endothelial dystrophy; IOP, intraocular pressure; PBK, pseudophakic bullous keratopathy; PPC, pseudophakic, posterior chamber.