Cox proportional hazards regression model in retinoblastoma eyes for association of retinoblastoma clinical features with local treatment failure
| Variable | Eyes in category, no (total=592) | Reference | HR (95% CI) | P value |
| (A) Univariate analysis | ||||
| Diffuse seeding | n=449 | Focal seeding | 2.80 (1.89 to 4.14) | <0.001 |
| Unilateral | n=213 | Bilateral | 1.85 (1.40 to 2.42) | <0.001 |
| SRF >5 mm | n=355 | SRF <5 mm | 2.20 (1.64 to 2.95) | <0.001 |
| Sphere | n=37 | Dust | 1.77 (1.05 to 2.97) | 0.031 |
| Cloud | n=115 | Dust | 1.00 (0.64 to 1.55) | >0.99 |
| (B) Multivariate analysis | ||||
| Diffuse | n=449 | Focal | 1.64 (1.20 to 2.26) | 0.002 |
| Unilateral | n=213 | Bilateral | 1.76 (1.34 to 2.31) | <0.001 |
| SRF >5 mm | n=355 | SRF <5 mm | 2.20 (1.45 to 3.35) | <0.001 |
SRF, subretinal fluid.