Patients’ characteristics (n=101)
Characteristic | Value |
Sex (n) | |
Male | 55 |
Female | 46 |
Age (years) | |
Median (range) | 69.47 (26.48–91.26) |
ECOG Performance Status (n) | |
0 | 69 |
1 | 22 |
2 | 9 |
3 | 1 |
4 | 0 |
5 | 0 |
Hypertension (n) | |
Yes | 62 |
No | 39 |
Diabetes mellitus (n) | |
Yes | 13 |
No | 88 |
Follow-up (months) | |
Mean (SD) | 34.56 (±14.70) |
Median (range) | 31.97 (2.53–75.99) |
Location (n) | |
Choroidal | 90 |
Ciliochoroidal | 11 |
Affected eye (n) | |
Left | 56 |
Right | 45 |
Affected eye segments (n)14 | |
3 affected eye segments | 44 |
>3 affected eye segments | 57 |
Location specifications (n) | |
Juxtapapillary | 45 |
Initial characteristics (n) | |
Subretinal fluid at diagnosis | 71 |
Macular oedema at diagnosis | 9 |
Orange pigment at diagnosis | 16 |
Conversion from nevus | 9 |
Tumour thickness (mm) | |
Mean (SD) | 5.99 (±3.75) |
Median (range) | 5.03 (0.87–15.52) |
Largest basal diameter (mm) | |
Mean (SD) | 11.06 (±4.03) |
Median (range) | 10.00 (3.00–20.00) |
Gross tumour volume (cm³) at diagnosis | |
Mean (SD) | 0.60 (± 0.57) |
Median (range) | 0.42 (0.18–2.60) |
Planning target volume (cm³) | |
Mean (SD) | 1.75 (± 1.18) |
Median (range) | 1.34 (0.33–5.66) |
Tumor size (COMS29) (n) | |
Small | 30 |
Medium | 38 |
Large | 33 |
Clinical Stage Group (AJCC Cancer Staging Manual 8th ed, 201730) (n) | |
I | 38 |
IIA | 31 |
IIB | 14 |
IIIA | 12 |
IIIB | 6 |
T category (AJCC Cancer Staging Manual 8th ed, 201730) (n) | |
T1 | 38 |
T2 | 33 |
T3 | 18 |
T4 | 12 |
Endoresection after radiotherapy (n) | |
Yes | 19 |
No | 82 |
Complications (n) | |
Cataract progression | 71 |
Neovascular glaucoma | 21 |
Rubeosis iridis | 24 |
Keratopathy | 40 |
Macular oedema | 20 |
Hyphema | 3 |
Vitreous haemorrhage | 12 |
Retinopathy | 14 |
Optic neuropathy | 8 |
Radiation scarring | 32 |
Sicca symptoms | 18 |
Overall survival (n) | |
Death | 20 |
Disease-specific death | 8 |
Local recurrence | 6 |
Metastasis | 12 |
Enucleation | 7 |
AJCC, American Joint Committee on Cancer; COMS, Collaborative Ocular Melanoma Study; ECOG, Eastern Cooperative Oncology Group; n, number of patients; SD, standard deviation.