Table 1

Patients’ characteristics (n=101)

CharacteristicValue
Sex (n)
 Male55
 Female46
Age (years)
 Median (range)69.47 (26.48–91.26)
ECOG Performance Status (n)
 069
 122
 29
 31
 40
 50
Hypertension (n)
 Yes62
 No39
Diabetes mellitus (n)
 Yes13
 No88
Follow-up (months)
 Mean (SD)34.56 (±14.70)
 Median (range)31.97 (2.53–75.99)
Location (n)
 Choroidal90
 Ciliochoroidal11
Affected eye (n)
 Left56
 Right45
Affected eye segments (n)14
 3 affected eye segments44
 >3 affected eye segments57
Location specifications (n)
 Juxtapapillary45
Initial characteristics (n)
 Subretinal fluid at diagnosis71
 Macular oedema at diagnosis9
 Orange pigment at diagnosis16
 Conversion from nevus9
Tumour thickness (mm)
 Mean (SD)5.99 (±3.75)
 Median (range)5.03 (0.87–15.52)
Largest basal diameter (mm)
 Mean (SD)11.06 (±4.03)
 Median (range)10.00 (3.00–20.00)
Gross tumour volume (cm³) at diagnosis
 Mean (SD)0.60 (± 0.57)
 Median (range)0.42 (0.18–2.60)
Planning target volume (cm³)
 Mean (SD)1.75 (± 1.18)
 Median (range)1.34 (0.33–5.66)
Tumor size (COMS29) (n)
 Small30
 Medium38
 Large33
Clinical Stage Group (AJCC Cancer Staging Manual 8th ed, 201730) (n)
 I38
 IIA31
 IIB14
 IIIA12
 IIIB6
T category (AJCC Cancer Staging Manual 8th ed, 201730) (n)
 T138
 T233
 T318
 T412
Endoresection after radiotherapy (n)
 Yes19
 No82
Complications (n)
 Cataract progression71
 Neovascular glaucoma21
 Rubeosis iridis24
 Keratopathy40
 Macular oedema20
 Hyphema3
 Vitreous haemorrhage12
 Retinopathy14
 Optic neuropathy8
 Radiation scarring32
 Sicca symptoms18
Overall survival (n)
 Death20
 Disease-specific death8
 Local recurrence6
 Metastasis12
 Enucleation7
  • AJCC, American Joint Committee on Cancer; COMS, Collaborative Ocular Melanoma Study; ECOG, Eastern Cooperative Oncology Group; n, number of patients; SD, standard deviation.