Demographic and ocular characteristics of the study population
| Groups (eyes) | Acute (n=25) | Non-acute (n=23) | Normal (n=34) | P value |
| Age, median (IQR), years | 56 (50–61.5) | 52 (46–57) | 52 (50–61) | 0.155 |
| Sex (male/female) | 18/7 | 15/8 | 15/19 | 0.074 |
| BCVA, logMAR, median (IQR) | 0.10 (0.00–0.61) | 0.22 (0.00–0.40) | 0.00 (0.00–0.00) | 0.000 |
| Spherical equivalent, median (IQR) | 0.00 (0.56–1.38) | 0.00 (0.50–0.50) | 0.00 (0.56–0.72) | 0.784 |
| Axial length, mean (SD), mm | 22.61±0.93 | 22.75±0.63 | 23.44±1.03 | 0.001 |
| C/D, median (IQR) | 0.00 (0.00–0.07) | 0.25 (0.00–0.55) | 0.48 (0.33–0.64) | 0.000 |
| Vertical C/D ratio, median (IQR) | 0.00 (0.00–0.05) | 0.22 (0.00–0.52) | 0.46 (0.31–0.59) | 0.000 |
| RNFL thickness, median (IQR), μm | 217.00 (184.00–325.00) | 68.00 (57.00–91.00) | 104.50 (100.00–111.25) | 0.000 |
| Cup area, median (IQR), mm2 | 0.00 (0.00–0.02) | 0.15 (0.00–0.67) | 0.45 (0.20–0.93) | 0.000 |
| Cup volume, median (IQR), mm3 | 0.000 (0.000–0.001) | 0.008 (0.000–0.264) | 0.300 (0.053–0.904) | 0.000 |
| Optic disc area, median (IQR), mm2 | 4.70 (3.52–5.36) | 2.61 (2.02–2.96) | 2.17 (1.90–2.57) | 0.000 |
| RIM area, median (IQR), mm2 | 4.68 (3.52–5.36) | 2.12 (1.64–2.45) | 1.64 (1.44–1.88) | 0.000 |
| Hypertension (yes/no) | 12/13 | 8/15 | 16/18 | 0.581 |
| Diabetes (yes/no) | 10/15 | 4/19 | 5/29 | 0.056 |
Data are presented as mean±SD or median (IQR). Differences were considered statistically significant at p<0.05.
BCVA, best-corrected visual acuity; C/D, cup/disc; LogMAR, logarithm of the minimum angle of resolution; RNFL, retinal nerve fibre layer.