Risk factors | Number of patients (%) |
Prior vegetative trauma | 12 (30.0%) |
Corneal transplantation | 7 (17.5%) |
Associated systemic comorbidities | |
Postrenal transplantation | 1 (2.5%) |
Chemotherapy for renal carcinoma | 1 (2.5%) |
Vitamin A deficiency | 2 (5.0%) |
Other systemic diseases | 3 (7.5%) |
Poor ocular surface | |
Post-Steven-Johnson syndrome | 1 (2.5%) |
Postchemical injury | 2 (5.0%) |
Decompensated cornea | 1 (2.5%) |
Previous history of ocular surgery | |
Paediatric lens aspiration | 1 (2.5%) |
Postcorneal tear repair | 1 (2.5%) |
Nasolacrimal duct obstruction | 1 (2.5%) |
Total | 33 (82.5%) |
Prior topical medication | |
Steroids | 7 (17.5%) |
Antibiotics | 3 (7.5%) |
Gatifloxacin 0.3% | 1 (2.5%) |
Ofloxacin 0.3% | 2 (5.0%) |
Moxifloxacin 0.5% | 1 (2.5%) |
Moxifloxacin 0.5% + tobramycin 0.3% | 5 (12.5%) |
Antifungal (natamycin 5%) | 7 (17.5%) |
Combination of topical antibiotics (gatifloxacin 0.3%: n=2; moxifloxacin 0.5%: n=5) and antifungal | 8 (20.0%) |
Cocktail of various topical medications (antibiotics, antifungal, antivirals, lubricants) | 8 (20.0%) |
Total | 34 (85.0%) |
Clinical features | |
Mean duration of symptoms (days) | 20.2±18.6* |
Best-corrected visual acuity | |
≥20/200 | 9 (22.5 %) |
CF | 8 (20.0%) |
HM+ | 15 (37.5%) |
PL+PR inaccurate | 8 (20.0%) |
Size of the infiltrate | |
Small (<6 mm) | 22 (55.0%) |
Large (>6 mm) | 18 (45.0%) |
Depth of the infiltrate | |
Superficial stromal | 11 (27.5%) |
Mid stromal | 9 (22.5%) |
Deep stromal | 15 (37.5%) |
>60% thinning | 6 (15.0%) |
Perforated | 5 (12.5%) |
Hypopyon | |
Absent | 20 (50.0%) |
<4 mm | 10 (25.0%) |
>4 mm | 3 (7.5%) |
Could not be ascertained (near total/total infiltrate) | 7 (17.5%) |
*Range: 1–75 days; median: 14 days.