Table 3

The univariate and multivariate analysis of relationship between demographic and biochemical characteristics and average RNFL thickness

VariablesUnivariate analysisMultivariate
BSEP valueBSEP value
Age (years)−0.2330.016 <0.001 −0.2600.024 <0.001
Gender (female vs male)2.0430.346 <0.001 1.7720.495 <0.001
High educational level−0.5760.9730.554
Smoking status1.3690.394 <0.001 −0.3190.5520.563
Body mass index (kg/m2)*
 <21−1.5310.643 0.017 −0.8220.6900.234
 27–300.7450.426 0.080 0.6680.4610.147
 ≥301.1440.537 0.033 1.4030.593 0.018
Diastolic >140 (mm Hg)2.2877.2220.751
Systolic >90 (mm Hg)7.9035.8970.180
Diabetes2.8880.929 0.002 2.5760.992 0.009
HbA1c (%)−0.4120.5160.425
HDL (normal vs abnormal)0.0280.3830.942
LDL (normal vs abnormal)0.4140.3680.260
TG (normal vs abnormal)0.1650.3980.678
Coronary heart disease2.2480.677 <0.001 0.5620.7060.426
Cataract extraction−4.5911.419 0.001 −5.8451.633 <0.001
Intraocular pressure (mm Hg)−0.1100.054 0.043 −0.1570.059 0.007
Spherical equivalent0.7340.076 <0.001 0.8620.108 <0.001
Axial length−0.5130.112 <0.001 −0.2400.121 0.048
BCVA (logMAR)−4.2700.593 <0.001 −0.7030.7240.331
  • Values with statistical significance are shown in boldface.

  • *21-27 (kg/m2) was set as the reference category.

  • BCVA, best-corrected visual acuity; HbA1c, glycosylated hemoglobin; HDL, high density lipoprotein; LDL, Low Density Lipoprotein; RNFL, retinal nerve fibre layer; TG, triglyceride.