Predictors associated with failure using Cox proportional hazards model
| Univariate | Multivariate* | |||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Intervention (LPI vs CLE) | 2.48 (1.89 to 3.25) | <0.001 | 2.52 (1.92 to 3.31) | <0.001 |
| Age (per 10 years older) | 1.12 (0.97 to 1.30) | 0.135 | 1.13 (0.97 to 1.31) | 0.107 |
| Female | 1.01 (0.79 to 1.30) | 0.945 | 1.01 (0.79 to 1.30) | 0.932 |
| Non-Chinese | 1.49 (1.11 to 2.00) | 0.008 | 1.52 (1.14 to 2.05) | 0.005 |
| PACG (vs PAC) | 1.27 (0.98 to 1.65) | 0.069 | 1.19 (0.92 to 1.55) | 0.193 |
| PAS (per 30° increase) | 0.81 (0.61 to 1.07) | 0.142 | 0.87 (0.65 to 1.16) | 0.335 |
| ACD (per 0.1 mm shorter) | 0.98 (0.95 to 1.01) | 0.309 | 0.99 (0.95 to 1.03) | 0.566 |
| Glaucoma medication at baseline | 1.37 (1.04 to 1.80) | 0.024 | 1.48 (1.12 to 1.95) | 0.006 |
| Visual field MD (per 1 dB worsen) | 1.01 (0.99 to 1.03) | 0.321 | 1.02 (0.99 to 1.04) | 0.166 |
| Visual acuity (per 1 line worsen) | 1.00 (0.96 to 1.05) | 0.950 | 1.00 (0.96 to 1.05) | 0.971 |
| IOP (per 5 mm Hg higher) | 1.07 (0.99 to 1.15) | 0.070 | 1.08 (1.01 to 1.16) | 0.029 |
Failure is defined as intraocular pressure (IOP)>21 or needing medication or surgery.
*All multivariate analyses adjusted for intervention, age, gender and race.
ACD, anterior chamber depth; CLE, clear lens extraction; LPI, laser peripheral iridotomy; MD, mean deviation; PAC, primary angle closure; PACG, primary angle closure glaucoma; PAS, peripheral anterior synechiae.