Multivariate analyses for baseline predictive factors of good response (intraocular pressure (IOP)<21, no additional surgery) and optimal response (IOP<21, on no medications and no additional surgery) at long-term follow-up (36 months)
| Good response (IOP<21 mm Hg and no surgery) | Optimal response (IOP<21 mm Hg and no medication or surgery) | |||
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Lens extraction (vs LPI) | 4.90 (1.01 to 3.57) | 0.046 | 10.13 (6.10 to 16.83) | <0.001 |
| Age (per 10 years older) | 0.88 (0.64 to 1.20) | 0.412 | 0.82 (0.61 to 1.10) | 0.191 |
| Female | 0.66 (0.38 to 1.12) | 0.121 | 1.17 (0.72 to 1.91) | 0.531 |
| Chinese | 1.68 (0.92 to 3.08) | 0.094 | 2.26 (1.31 to 3.89) | 0.003 |
| PAC (vs PACG) | 0.93 (0.54 to 1.59) | 0.785 | 2.10 (1.26 to 3.49) | 0.005 |
| PAS (per 30° increase) | 1.18 (0.64 to 2.18) | 0.596 | 1.49 (0.86 to 2.58) | 0.156 |
| Irido-trabecular contact (per 30°) | 1.01 (0.90 to 1.12) | 0.915 | 1.02 (0.93 to 1.13) | 0.632 |
| Axial length (per 1 mm shorter) | 1.23 (0.93 to 1.61) | 0.147 | 1.15 (0.88 to 1.51) | 0.297 |
| ACD (per 0.1 mm shorter) | 1.04 (0.96 to 1.12) | 0.322 | 1.05 (0.97 to 1.13) | 0.209 |
| Spherical equivalence (+1 D) | 1.03 (0.91 to 1.16) | 0.673 | 1.01 (0.91 to 1.14) | 0.810 |
| No glaucoma medication | 1.39 (0.79 to 2.44) | 0.259 | 2.77 (1.61 to 4.78) | <0.001 |
| Visual field MD (per 1 dB better) | 1.02 (0.97 to 1.07) | 0.425 | 1.06 (1.01 to 1.12) | 0.022 |
| Visual acuity (per 1 line worsen) | 0.96 (0.87 to 1.05) | 0.348 | 0.94 (0.85 to 1.03) | 0.190 |
| IOP (per 5 mm Hg lower) | 1.21 (1.02 to 1.42) | 0.026 | 0.93 (0.79 to 1.08) | 0.333 |
*All multivariate analyses adjusted for lens extraction, age, gender, ethnicity.
ACD, anterior chamber depth; LPI, laser peripheral iridotomy; MD, mean deviation; PAC, primary angle closure; PACG, primary angle closure glaucoma; PAS, peripheral anterior synechiae.