Table 5

Multivariate analyses for baseline predictive factors of good response (intraocular pressure (IOP)<21, no additional surgery) and optimal response (IOP<21, on no medications and no additional surgery) at 36 months, by treatment arm

	Clear lens extraction				Laser peripheral iridotomy
	Good response		Optimal response		Good response		Optimal response
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Age (per 10 years older)	1.22 (0.66 to 2.25)	0.524	0.86 (0.58 to 1.28)	0.455	0.77 (0.53 to 1.11)	0.165	0.72 (0.45 to 1.15)	0.173
Female	0.49 (0.17 to 1.44)	0.194	0.84 (0.45 to 1.60)	0.602	0.75 (0.40 to 1.40)	0.372	2.00 (0.88 to 4.57)	0.100
Chinese	---	---	1.89 (0.90 to 3.97)	0.092	1.09 (0.55 to 2.13)	0.812	2.76 (1.26 to 6.05)	0.011
PAC (vs PACG)	0.79 (0.29 to 2.11)	0.633	1.42 (0.73 to 2.75)	0.299	1.09 (0.58 to 2.06)	0.787	3.80 (1.67 to 8.63)	0.001
PAS (per 30° increase)	2.23 (0.61 to 8.18)	0.228	1.80 (0.85 to 3.82)	0.126	1.03 (0.50 to 2.11)	0.934	1.14 (0.48 to 2.67)	0.771
Irido-trabecular contact (per 30°)	1.11 (0.94 to 1.32)	0.212	0.98 (0.86 to 1.10)	0.717	0.97 (0.85 to 1.12)	0.715	1.15 (0.94 to 1.40)	0.171
Axial length (per 1 mm shorter)	1.41 (0.80 to 2.48)	0.239	1.42 (0.97 to 2.07)	0.070	1.15 (0.84 to 1.58)	0.374	0.94 (0.63 to 1.40)	0.761
ACD (per 0.1 mm shorter)	1.18 (1.02 to 1.36)	0.030	1.09 (0.99 to 1.21)	0.090	1.00 (0.92 to 1.09)	0.926	1.00 (0.90 to 1.10)	0.941
Spherical equivalence (+1 D)	1.02 (0.83 to 1.25)	0.848	1.13 (0.97 to 1.31)	0.105	1.00 (0.86 to 1.15)	0.952	0.86 (0.70 to 1.05)	0.137
No glaucoma medication	1.09 (0.40 to 2.97)	0.868	2.25 (1.12 to 4.54)	0.024	1.44 (0.73 to 2.86)	0.297	4.62 (1.86 to 11.48)	0.001
Visual field MD (per 1 dB better)	0.90 (0.78 to 1.02)	0.109	1.05 (0.99 to 1.12)	0.122	1.05 (0.99 to 1.12)	0.092	1.12 (1.00 to 1.25)	0.045
Visual acuity (per 1 line worsen)	1.00 (0.83 to 1.22)	0.972	0.88 (0.77 to 1.00)	0.048	0.96 (0.86 to 1.08)	0.516	1.03 (0.89 to 1.18)	0.712
IOP (per 5 mm Hg lower)	0.97 (0.71 to 1.34)	0.861	1.13 (0.93 to 1.38)	0.224	1.30 (1.05 to 1.60)	0.017	1.02 (0.80 to 1.30)	0.876

*All multivariate analyses adjusted for age, gender (and Chinese).
ACD, anterior chamber depth; MD, mean deviation; PAC, primary angle closure; PACG, primary angle closure glaucoma; PAS, peripheral anterior synechiae.