Baseline characteristics of all participants, RVO exposed and never-exposed
| All | RVO exposed | Never exposed | |
| (N=4 194 781) | (n=15 665) | (n=4,179,116) | |
| Sex | |||
| Men | 2 054 446 (49.0) | 7729 (49.3) | 2 046 717 (49.0) |
| Women | 2 140 335 (51.0) | 7936 (50.7) | 2 132 399 (51.0) |
| Age at index date, years | 45.6 (40.0–59.9) | 58.8 (49.9–67.7) | 45.6 (40.0–59.9) |
| Age at RVO diagnosis, years | 71.8 (63.0–79.4) | 71.8 (63.0–79.4) | NA |
| No of incident RVO diagnoses, mean no per year | |||
| 1998–2010 | 547 | 547 | NA |
| 2011–2018 | 1070 | 1070 | NA |
| Charlson Comorbidity Index score | |||
| 0 (low) | 3 781 035 (90.1) | 13 961 (89.1) | 3 767 074 (90.1) |
| 1 | 172 558 (4.1) | 746 (4.8) | 171 812 (4.1) |
| 2 | 190 059 (4.5) | 774 (4.9) | 189 285 (4.5) |
| >3 (high) | 51 129 (1.2) | 184 (1.2) | 50 945 (1.2) |
| Comorbid conditions | |||
| Arterial hypertension | 1 479 292 (35.3) | 10 866 (69.4) | 1 468 426 (35.1) |
| Dyslipidaemia | 1 067 567 (25.4) | 7907 (50.5) | 1 059 660 (25.4) |
| Diabetes | 451 372 (10.8) | 2913 (18.6) | 448 459 (10.7) |
| Smoking-related disorders | 239 047 (5.7) | 1569 (10.0) | 237 478 (5.7) |
Data presented as median (25%–75% percentile) for continuous variables and count (%) for categorical variables.
NA, not applicable; RVO, retinal vein occlusion.