Summary of ophthalmic manifestations of Williams-Beuren syndrome in the literature
| Greenberg et al, 20 1988 | Winter et al,22 1996 | Castelo-Branco et al,11 2007 | Weber et al,23 2014 | Viana et al,21 2015 | Our cohort | |||||||
| No of patients in study | 42 | 152 | 13 | 30 | 16 | 57 | ||||||
| Age range | 3 months to 43 years | 6 months to 46 years | 10 to 31 years | 7 to 26 years | 5 to 40 years | 3 to 60 years | ||||||
| Hyperopia (N, %) | 41/42 | 98% | 17/25 | 68% | Moderate | – | 20/30 | 67% | 6/16 | 38% | 10/57 | 18% |
| Strabismus (N, %) | 12/42 | 29% | 82/152 | 54% | 4/13 | 31% | 11/30 | 37% | 3/16 | 19% | 17/57 | 30% |
| Stellate Iris (N, %) | 29/42 | 69% | 112/152 | 74% | 11/13 | 85% | 3/30 | 10% | 13/16 | 81% | 30/57 | 53% |
| Optic disc abnormalities (N, %) | 18/33 | 55% | 8/46 | 17% | 5/13 | 38% | – | – | 3/16 | 19% | 16/114 | 14% |
| Tortuous retinal vessels (N, %) | 0/33 | 0% | 10/46 | 22% | – | – | 8/30 | 27% | 6/16 | 38% | 51/57 | 90% |