Demographic, visual field and circumpapillary retinal nerve fibre layer (cpRNFL) thickness characteristics of the participants
| Variables | APAC N=40 | POAG N=65 | Controls N=44 | P value | |||
| Among* 3 groups | APAC† versus controls | POAG† versus controls | APAC† versus POAG | ||||
| Age, year, (mean±SD) | 62±7 | 59±12 | 65±6 | 0.001 | 0.396 | 0.001 | 0.161 |
| Female, n (%) | 30 (75.00) | 34 (52.31) | 17 (38.64) | 0.003 | |||
| Axial length, mm (mean±SD) | 22.71±1.16 | 23.92±1.04 | 22.98±1.18 | <0.001 | 0.815 | 0.001 | <0.001 |
| VF MD, dB (median (IQR)) | −4.09 (−4.52 to 2.78) | −5.02 (−8.62 to 3.02) | −1.80 (−3.67 to 0.11) | <0.001 | 0.008 | <0.001 | 0.019 |
| VF PSD, dB (median (IQR)) | 2.63 (1.90–5.00) | 6.66 (3.36–11.63) | 2.14 (1.98–3.43) | <0.001 | 0.147 | <0.001 | <0.001 |
| Visual Field Index, % (median (IQR)) | 98 (96–99) | 89.5 (79–96) | – | <0.001 | – | – | <0.001 |
| Average cpRNFL, μm (median (IQR)) | 98 (87–103) | 83.5 (71.5–95.0) | 102.5 (95–108) | <0.001 | 0.013 | <0.001 | <0.001 |
| Superior cpRNFL, μm (median (IQR)) | 116 (93–127) | 108 (92.5–119.25) | 127.5 (117–141) | <0.001 | <0.01 | <0.001 | 0.051 |
| Inferior cpRNFL, μm (median (IQR)) | 112.5 (92–126) | 88.5 (70.75–107.05) | 132.5 (125–145) | <0.001 | 0.003 | <0.001 | 0.008 |
| Nasal cpRNFL, μm (median (IQR)) | 75. (66–88.5) | 70.25 (58.25–78.75) | 86 (79.5–96) | <0.001 | <0.001 | <0.001 | 0.003 |
| Temporal cpRNFL, μm (median (IQR)) | 76 (66.5–84) | 69.25 (59.75–75) | 79.5 (71.5–84) | <0.001 | 0.191 | <0.001 | 0.001 |
The participants’ eye baseline clinical data per group are reported as mean±SD and median with IQR. Categorical variables: χ2 test.
*P values represent comparisons between APAC, POAG and control groups using ANOVA.
†P value represent pairwise comparison between each groups using Bonferroni correction or Dunn’s test.
ANOVA, analysis of variance; APAC, acute primary angle closure; MD, mean deviation; POAG, primary open-angle glaucoma; PSD, pattern SD; VF, visual field.