Table 3

Postoperative endothelial cell loss after deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in keratoconus eyes

OutcomesDALK group
Big bubble-DALK subgroup (n=118)Manual dissection-DALK subgroup (n=110)PK group
P value (DALK versus PK)
Percentage of endothelial cell loss per year
Early phase−9.2 (7.5)−8.6 (6.6)*−9.7 (6.6)*−16.9 (12.7)<0.00001
Late phase−2.3 (3.0)−2.2 (2.7)*−2.3 (3.2)*−5.5 (4.3)<0.00001
Endothelial cell loss (cells/mm2) per year
Early phase−214 (460)−190 (576)*236 (456)*−593 (692)<0.00001
Late phase−52 (134)−48 (152)*−54 (127)*−100 (126)<0.00001
  • Slopes were calculated using the biphasic linear model with a change in slope at 1 year postoperatively. Shown is the mean (SD)

  • *p<0.05 versus PK group.