OCTA metrics between PA and HC
| Variables | HC (n=184) | PA (n=99) | β coefficient (95% CI) | P value |
| DCP | ||||
| FAZ area (mm2) | 1.27 (0.29) | 1.14 (0.28) | −0.121 (–0.189 to –0.035) | 0.001** |
| FAZ perimeter (mm) | 4.35 (0.56) | 4.02 (0.54) | −0.310 (–0.441 to –0.180) | <0.001*** |
| FAZ circularity | 0.84 (0.08) | 0.88 (0.05) | 0.037 (0.020 to 0.054) | <0.001*** |
| FAZ AR | 1.30 (0.13) | 1.30 (0.13) | −0.001 (–0.033 to 0.032) | 0.976 |
| PD centre region (%) | 25.41 (4.73) | 28.56 (11.34) | 3.237 (1.333 to 5.141) | 0.001** |
| PD inner ring (%) | 48.86 (1.59) | 49.04 (1.84) | 0.197 (–0.218 to 0.612) | 0.350 |
| PD outer ring (%) | 49.85 (1.01) | 50.18 (1.05) | 0.349 (0.097 to 0.602) | 0.007** |
| SCP | ||||
| FAZ area (mm2) | 0.37 (0.12) | 0.34 (0.12) | −0.026 (–0.054 to 0.003) | 0.074 |
| FAZ perimeter (mm) | 2.26 (0.37) | 2.14 (0.38) | −0.100 (–0.199 to –0.011) | 0.028* |
| FAZ circularity | 0.90 (0.03) | 0.91 (0.04) | 0.015 (0.006 to 0.023) | 0.001** |
| FAZ AR | 1.17 (0.11) | 1.17 (0.11) | 0.004 (–0.022 to 0.031) | 0.738 |
| PD centre region (%) | 23.63 (5.04) | 26.58 (11.82) | 2.858 (0.883 to 4.833) | 0.005** |
| PD inner ring (%) | 39.65 (2.35) | 40.25 (4.51) | 0.573 (–0.232 to 1.378) | 0.162 |
| PD outer ring (%) | 44.97 (1.44) | 45.34 (2.08) | 0.365 (–0.054 to 0.785) | 0.087 |
Mean (SD). A comparison of OCTA metrics between PA and HC. Linear regressions were performed between the PA and HC. Age and gestational age were adjusted as covariates.
*P<0.05, **P<0.01, ***P<0.001.
AR, aspect ratio; DCP, deep capillary plexus; FAZ, foveal avascular zone; HC, healthy control; OCTA, optical coherence tomography angiography; PA, pregnant patients with anaemia; PD, perfusion density; SCP, superficial capillary plexus.