Table 3

Topographic characteristics of choroid and retina in TAO patients and healthy controls

9 Zones	5 Layers	Active (n=38)		Inactive (n=22)		NC (n=67)		Total (n=127)		P active versus inactive	P active versus NC	P inactive versus NC
Sub field	Thickness	Mean	SD	Mean	SD	Mean	SD	Mean	SD
Central fovea	Choroid	276	84	225	112	224	79	240	89	<0.05*	＜0.01**	1.00
	Retina	254	60	255	23	250	44	252	46	0.97	0.96	0.17
	GCL+	53	14	55	12	53	18	53	16	1.00	1.00	0.42
	GCL++	66	31	64	19	65	36	65	32	1.00	1.00	0.75
	RNFL	13	20	10	8	12	20	12	18	1.00	1.00	1.00
Inner temperal	Choroid	284	88	230	106	89	9	248	88	0.07	＜0.05*	1.00
	Retina	297	59	296	17	295	25	296	38	0.37	1.00	0.87
	GCL+	82	13	85	12	83	12	83	12	0.46	1.00	1.00
	GCL++	109	20	107	14	109	15	108	17	1.00	1.00	1.00
	RNFL	27	14	22	5	26	15	26	14	1.00	1.00	1.00
Inner superial	Choroid	275	77	229	109	60	10	247	85	0.06	0.07	1.00
	Retina	307	33	313	19	313	45	311	38	0.14	0.88	0.59
	GCL+	87	8	87	11	87	11	87	10	1.00	1.00	1.00
	GCL++	120	12	124	14	126	29	124	23	0.25	0.41	1.00
	RNFL	33	9	37	9	39	24	37	19	0.16	0.28	1.00
Inner nasal	Choroid	257	83	203	114	205	85	220	93	＜0.05*	＜0.05*	1.00
	Retina	307	28	313	21	310	23	310	24	0.17	1.00	0.59
	GCL+	87	10	89	13	89	9	89	10	0.38	0.55	1.00
	GCL++	118	14	119	17	120	14	119	14	0.30	0.22	1.00
	RNFL	31	13	30	10	31	13	31	12	1.00	1.00	1.00
Inner inferial	Choroid	272	85	219	120	218	82	235	93	＜0.05*	＜0.01**	1.00
	Retina	295	31	301	16	300	16	298	22	0.58	0.37	1.00
	GCL+	78	16	86	11	85	10	83	13	0.13	0.07	1.00
	GCL++	111	18	112	17	117	15	114	16	1.00	0.27	1.00
	RNFL	33	19	26	8	31	12	31	14	0.47	1.00	0.18
Outer temperal	Choroid	279	83	230	92	234	71	247	81	0.07	＜0.05*	1.00
	Retina	260	41	261	18	254	18	257	27	1.00	1.00	0.58
	GCL+	68	10	69	8	66	9	67	9	1.00	1.00	0.88
	GCL++	96	14	95	11	93	10	94	11	1.00	1.00	1.00
	RNFL	28	9	26	6	27	9	27	9	0.95	0.50	1.00
Outer superial	Choroid	268	72	225	96	242	71	247	77	0.11	0.38	0.91
	Retina	275	41	270	16	275	49	274	43	1.00	1.00	1.00
	GCL+	64	10	59	8	61	10	62	10	0.53	1.00	1.00
	GCL++	109	15	107	12	113	28	111	23	1.00	0.62	0.28
	RNFL	45	10	47	9	51	22	49	18	0.95	＜0.05*	1.00
Outer nasal	Choroid	215	79	168	116	167	86	182	92	＜0.05*	＜0.05*	1.00
	Retina	286	24	285	16	285	18	285	19	1.00	1.00	1.00
	GCL+	68	9	65	13	66	9	66	9	1.00	0.78	1.00
	GCL++	123	13	121	13	124	11	123	12	1.00	1.00	1.00
	RNFL	55	14	56	15	59	12	57	13	1.00	0.11	0.67
Outer inferial	Choroid	264	80	205	114	210	80	225	90	＜0.01**	＜0.01**	1.00
	Retina	264	27	265	19	259	17	262	21	1.00	0.53	0.52
	GCL+	60	13	63	10	60	10	60	11	1.00	1.00	0.92
	GCL++	108	12	108	12	107	10	107	11	1.00	1.00	1.00
	RNFL	48	12	46	10	47	9	47	10	0.60	1.00	0.65
Average thickness	Choroid	261	76	210	103	216	74	228	82	＜0.05*	＜0.05*	1.00
	Retina	278	31	277	14	276	21	277	23	1.00	1.00	1.00
	GCL+	69	6	69	7	68	6	68	6	1.00	1.00	1.00
	GCL++	109	11	108	11	110	11	109	11	1.00	1.00	1.00
	RNFL	40	9	40	8	42	10	41	9	1.00	0.57	0.31

*p<0.05，**p<0.01, ***p<0.001
GCL, Ganglion cell layer; RNFL, retinal nerve fiber layer; TAO, thyroid-associated ophthalmopathy.